122

Biochemistry

122.102 Biochemistry of Cells 15 credits
A foundation course that introduces molecular aspects of the cellular processes occurring in humans, animals, microbes and plants. An exploration of the molecules of life, proteins and enzymes in action, energy for living and energy storage with applications to the environment, health and disease, biotechnology, nutrition, sport and exercise. Theoretical aspects are supported by a practical laboratory programme.
122.222 Biochemistry for Technology 15 credits
A foundation course that introduces molecular aspects of the cellular processes occurring in humans, animals, microbes and plants. An exploration of the molecules of life, proteins and enzymes in action, energy for living and energy storage with applications to the environment, health and disease, biotechnology, nutrition, sport and exercise. Theoretical aspects are supported by a laboratory programme focused on proteins and enzymes and their uses in diagnosing disease.
122.231 Genes and Gene Expression 15 credits
Structure of DNA. Replication, DNA repair and transcription. Regulation of prokaryotic gene expression. Technologies used in the study of genes and gene expression: plasmids, sequencing, restriction enzymes, libraries, PCR, Southern, northern and western analysis, expression vectors and the production of recombinant proteins. A practical course that illustrates concepts presented in the lectures.
122.232 Protein Biochemistry 15 credits
Protein biosynthesis, structure and function. Topics will include protein translation, folding, targeting and post-translational modification, the relationship between protein structure and function, enzyme kinetics, mechanisms of enzyme catalysis and control, membranes and membrane proteins. Lectures will be complemented with a practical course focused on developing the appropriate skills to investigate proteins.
122.233 Metabolic Biochemistry 15 credits
Energy metabolism. Biosynthesis of carbohydrates and the metabolism of polysaccharides. Lipid metabolism. Nitrogen metabolism. Integration and regulation of carbohydrate, lipid and amino acid metabolism. Cellular communication systems.
122.303 Gene Regulation 15 credits
An advanced course on gene regulation. Topics include methods and experimental strategies for studying gene promoters and associated transcription factors, transcription initiation, transcription activation, role of chromatin structure in gene regulation, RNA processing, the role of non-coding RNA in gene expression and cytoplasmic control mechanisms.
122.322 Protein Structure and Function 15 credits
The structural and biochemical basis of protein function will be explored with an emphasis on techniques of protein isolation and purification, current methods of protein analysis, enzyme function and kinetics, protein folding and molecular interactions. A laboratory and computer-based practical course in protein purification and analysis reinforces the theoretical aspects of the course.
122.382 Clinical Biochemistry 15 credits
The biochemistry of human tissues with particular emphasis on disease detection. The practical course will include analytical methods and specialised techniques applied to clinical chemistry.
122.703 Gene Expression 30 credits
Advanced studies of selected topics in gene regulation at transcriptional and post-transcriptional levels.
122.704 Molecular Cell Biology 30 credits
Advanced studies of selected topics in biochemistry and cell biology
122.713 Advanced Topics in Biochemistry 15 credits
The course will involve use of the current literature to critically examine the experimental systems used to advance knowledge in Biochemistry.
122.798 Research Report 30 credits
122.870 Research Report 60 credits
122.871 Thesis 90 Credit Part 1 45 credits
A supervised and guided independent study resulting in a published work.
122.872 Thesis 90 Credit Part 2 45 credits
A supervised and guided independent study resulting in a published work
122.875 Thesis 90 credits
A supervised and guided independent study resulting in a published work.
122.897 Thesis 120 Credit Part 1 60 credits
A supervised and guided independent study resulting in a published work.
122.898 Thesis 120 Credit Part 2 60 credits
A supervised and guided independent study resulting in a published work.
122.899 Thesis 120 credits
A supervised and guided independent study resulting in a published work.
122.900 PhD Biochemistry 120 credits

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