The Middle-Eastern Women's Health Study

This study is now complete and the findings have been published in the scientfic journal, Nature.

For full results and publication please see here.

Summary:

Middle-Eastern female immigrants are at increased risk of vitamin D deficiency and their response to prescribed vitamin D dosages may not be adequate and affected by other factors.

Objectives:

1. To determine the likelihood of vitamin D deficiency and its determinants in Middle Eastern women living in Auckland, New Zealand

2. To determine vitamin D supplementation response to two different vitamin D doses.

To address both objectives, two separate studies were undertaken: 1. Forty three women aged ≥20 participated in a cross-sectional pilot study during winter 2. Sixty two women aged 20-50 years participated in a randomised, double-blind placebo-controlled trial consuming monthly either 50000, 100000IU vitamin D3 or placebo for 6 months (winter to summer).

Results:

All women in Study 1 and 60% women in Study 2 were measured as vitamin D deficient. The average vitamin D level increased in all groups. Only 32% and 67% achieved sufficient vitamin D levels with 50000 and 100000IU/month of supplementation, respectively.

Predictors of 6-months change in vitamin D status were dose, baseline vitamin D status and body fat percentage.

In conclusion, vitamin D deficiency/insufficiency is highly prevalent in this population. Monthly 100000IU vitamin D for 6 months is more effective than 50000IU in achieving a vitamin D level which would be classed as sufficient, however a third of women still did not achieve these levels.

 

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