College of Sciences staff

Contact details +64 (06) 356 9099  ext. 84737

Dr Rosemary Brown

Senior Tutor in Biochemistry and Genetics

Institute of Fundamental Sciences

Research Outputs

Journal

Wang, S., Haapalainen, AM., Yan, F., Du, Q., Tyler, PC., Evans, GB., . . . Schramm, VL. (2012). A picomolar transition state analogue inhibitor of MTAN as a specific antibiotic for helicobacter pylori. Biochemistry. 51(35), 6892-6894
[Journal article]Authored by: Brown, R., Norris, G.
Allen, KA., Brown, RL., Norris, G., Tyler, PC., Watt, DK., & Zubkova, OV. (2010). Syntheses of novel azasugar-containing mimics of heparan sulfate fragments as potential heparanase inhibitors. Carbohydrate Research. 345(13), 1831-1841
[Journal article]Authored by: Brown, R., Norris, G.
Anderson, AA., Brown, RL., Polster, B., Pollock, N., & Stowell, KM. (2008). Identification and biochemical characterization of a novel ryanodine receptor gene mutation associated with malignant hyperthermia. Anesthesiology. 108(2), 208-215
[Journal article]Authored by: Brown, R., Stowell, K.
Gutierrez, JA., Luo, M., Singh, V., Li, L., Brown, RL., Norris, GE., . . . Schramm, VL. (2007). Picomolar inhibitors as transition-state probes of 5′-methylthioadenosine nucleosidases. ACS Chemical Biology. 2(11), 725-734
[Journal article]Authored by: Brown, R., Norris, G.
Singh, V., Luo, M., Brown, RL., Norris, GE., & Schramm, VL. (2007). Transition-state structure of Neisseria meningitides 5′- methylthioadenosine/S-adenosylhomocysteine nucleosidase. Journal of the American Chemical Society. 129(45), 13831-13833
[Journal article]Authored by: Brown, R., Norris, G.
Ho, LW., Brown, RL., Maxwell, M., Wyttenbach, A., & Rubinsztein, DC. (2005). Wild type huntingtin reduces the cellular toxicity of mutant huntingtin in mammalian cell models of Huntington's disease. Journal of Medical Genetics. 38(7), 450-452
[Journal article]Authored by: Brown, R.
Sugars, KL., Brown, RL., Cook, LJ., Swartz, J., & Rubinsztein, DC. (2004). Decreased cAMP response element-mediated transcription. The Journal of Biological Chemistry. 279(6), 4988-4999
[Journal article]Authored by: Brown, R.
Davis, M., Brown, RL., Dickson, A., Horton, H., James, D., Laing, N., . . . Stowell, KM. (2002). Malignant hyperthermia associated with exercise-induced rhabdomyolysis or congenital abnormalities and a novel RYR1 mutation in New Zealand and Australian pedigrees. British Journal of Anaesthesia. 88(4), 508-515
[Journal article]Authored by: Brown, R.
Ariyaratne, KANS., Brown, R., Dasgupta, A., De Jonge, J., Jameson, GB., Loo, TS., . . . Norris, GE. (2002). Expression of bovine β-lactoglobulin as a fusion protein in Escherichia coli: A tool for investigating how structure affects function. International Dairy Journal. 12(4), 311-318
[Journal article]Authored by: Brown, R., Jameson, G., Loo, T., Norris, G.
Wyttenbach, A., Swartz, J., Kita, H., Thykjaer, T., Carmichael, J., Bradley, J., . . . Rubinsztein, DC. (2001). Polyglutamine expansions cause decreased CRE-mediated transcription and early gene expression changes prior to cell death in an inducible cell model of Huntington's disease. Human Molecular Genetics. 10(17), 1829-1845
[Journal article]Authored by: Brown, R.
Chamley, D., Pollock, AN., Stowell, KM., & Brown, RL. (2000). Malignant hyperthermia in infancy and identification of novel RYR1 mutation. British Journal of Anaesthesia. 84(4), 500-504
[Journal article]Authored by: Brown, R.
Brown, RL., Neil Pollock, A., Couchman, KG., Hodges, M., Hutchinson, DO., Waaka, R., . . . Stowell, KM. (2000). A novel ryanodine receptor mutation and genotype-phenotype correlation in a large malignant hyperthermia New Zealand Maori pedigree. Human Molecular Genetics. 9(10), 1515-1524
[Journal article]Authored by: Brown, R., Stowell, K.
Chamley, D., Pollock, NA., Stowell, KM., & Brown, RL. (2000). Malignant hyperthermia in infancy and identification of novel RYR1 mutation. British Journal of Anaesthesia. 84(4), 500-504
[Journal article]Authored by: Brown, R., Stowell, K.
Brown, RL., Baker, HM., Jameson, GB., Scopes, RK., & Baker, EN. (1996). Crystallization and preliminary X-ray diffraction studies of a cobalt-substituted derivative of the iron-dependent alcohol dehydrogenase from Zymomonas mobilis. Acta Crystallographica Section D: Biological Crystallography. 52(1), 218-220
[Journal article]Authored by: Brown, R., Jameson, G.
Baker, HM., Brown, RL., Dobbs, AJ., Blackwell, LF., Buckley, PD., Hardman, MJ., . . . Baker, EN. (1994). Crystallization and preliminary X-ray diffraction studies on cytosolic (Class 1) aldehyde dehydrogenase from sheep liver. Journal of Molecular Biology. 241(2), 263-264
[Journal article]Authored by: Brown, R.

Thesis

Brown, RL. (2000). A genetic test for malignant hyperthermia. (Doctoral Thesis, Massey University, Palmerston North)
[Doctoral Thesis]Authored by: Brown, R.

Conference

Baker, HM., Brown, RL., Dobbs, AJ., Kitson, KE., Kitson, TM., & Baker, EN.Crystallization of sheep liver cytosolic aldehyde dehydrogenase in a form suitable for high resolution X-ray structural analysis. Advances in Experimental Medicine and Biology. (pp. 67 - 70). 0065-2598.
[Conference]Authored by: Brown, R.

Other

Wang, S., Haapalainen, AM., Yan, F., Du, Q., Tyler, PC., Evans, GB., . . . Schramm, VL. (2012). 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase from H. pylori.
[Dataset]Authored by: Brown, R., Norris, G.Contributed to by: Norris, G.
Brown, RL., Anderson, BF., Tyler, PC., Evans, GB., Sutherland-Smith, AJ., & Norris, GE. (2012). S-Adenosylhomocysteine Nucleosidase from S. aureus.
[Dataset]Authored by: Brown, R., Norris, G., Sutherland-Smith, A.Contributed to by: Norris, G.
Ponniah, K., Norris, GE., Anderson, BF., Brown, RL., Tyler, PC., Evans, GB., . . . Frolich, R. (2012). Crystal structure of s-adenosylhomocysteine nucleosidase from streptococcus pyogenes in complex with 5-methylthiotubericidin;.
[Dataset]Authored by: Brown, R., Norris, G.Contributed to by: Norris, G.

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