College of Sciences staff

Associate Professor Evelyn Sattlegger staff profile picture

Contact details +64 (09) 414 0800  ext. 43502

Associate Professor Evelyn Sattlegger

Associate Professor

Institute of Natural and Mathematical Sciences

more information can be found at http://www.sattlegger-lab.webs.com


Roles and Responsibilities

Research and Teaching

More about me...View less...

Professional

Contact details

  • Ph: +64 (0)9 414 0800 extn 43502
    Location: 4, Building 14
    Campus: Albany

Qualifications

  • Vordiplom, equivalent to Bachelor of Science - Leibniz Uni., Medical & Veterin. School, Hannover (1988)
  • Diplom (Dist), Microb, Genetics, Biochem, Immunolo - Leibniz Uni., Medical & Veterin. School, Hannover (1992)
  • Doctor rerum naturalium, Molecular Biol & Genetics - Leibniz University Hannover (1996)

Research Expertise

Research Interests

Stress & starvation,

how do we (i.e. the cells in our body) respond and cope

Signal transduction mechanisms, and translational control

Using baker's yeast (Saccharomyces) as model organism for health related questions

Saccharomyces in Biotechnological applications

Techniques applied: Molecular Biology, Molecular Genetics, Genetics, Cell Biology, Biochemistry (protein purification, protein-protein/nucleic acid interactions, ribosomes, enzyme assays

Organisms: Saccharomyces cerevisiae (baker's or brewer's yeast), Neurospora crassa, Escherichia coli, cell culture

Thematics

21st Century Citizenship, Resource Development and Management, Health and Well-being, Future Food Systems

Area of Expertise

Field of research codes
Biochemistry and Cell Biology (060100): Biological Sciences (060000): Genetics (060400):
Medical And Health Sciences (110000):
Microbiology (060500): Other Biological Sciences (069900)

Keywords

yeast as model organism for biomedical investigations

molecular biology & genetics

Saccharomcyes cerevisae - baker's yeast

regulation of the protein Gcn2

Research Projects

Summary of Research Projects

Position Current Completed
Project Leader 3 19

Completed Projects

Project Title: How do we know that we are hungry? Unravelling the molecular basis of sensing amino acid starvation

Proper food selection is influenced not only by cultural and learning factors, but also by inherited factors. Two such factors, GCN2 and GCN1, are the focus of our work. GCN2 is an enzyme, and together with its effector protein GCN1, is essential for every eukaryotic cell to detect and cope with amino acid-starvation. Amino acids are particularly important nutrients because, as constituents of proteins, they execute almost all biological functions. GCN2 is also essential for further specialized processes such as developing aversion against amino acid-imbalanced food, long term memory formation, viral defence, and possibly silencing the immune system. Thus, GCN2 plays several pivotal roles in life, suggesting that GCN2-malfunction is implicated in associated diseases/disorders. GCN2¿s role in these various processes remains obscure, and GCN1-function has not been explored so far. In order to understand specialized processes involving GCN2, we first need to elucidate the universal cellular role of GCN2 and GCN1, i.e. sensing and signalling amino acid-hunger. We propose to unravel this GCN2/GCN1-function in molecular detail by using a simple eukaryotic model organism, baker¿s yeast, and following interdisciplinary approaches involving biochemistry, molecular biology, genetics, and cryo electron microscopy. Our research will pave the way to understanding the many specialized GCN2-functions.
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Date Range: 2007 - 2011

Funding Body: Royal Society of New Zealand

Project Team:

Project Title: Making an IMPACT on brain function

Studying the function of YIH1, the yeast homologue of the brain protein impact.
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Date Range: 2006 - 2010

Funding Body: Health Research Council of New Zealand

Project Team:

Research Outputs

Journal

Lee, SJ., Ramesh, R., de Boor, V., Gebler, JM., Silva, RC., & Sattlegger, E. (2017). Cost-effective and rapid lysis of Saccharomyces cerevisiae cells for quantitative western blot analysis of proteins, including phosphorylated eIF2α. Yeast. 34(9), 371-382
[Journal article]Authored by: Sattlegger, E.
Rakesh, R., Krishnan, R., Sattlegger, E., & Srinivasan, N. (2017). Recognition of a structural domain (RWDBD) in Gcn1 proteins that interacts with the RWD domain containing proteins. Biology Direct. 12(1)
[Journal article]Authored by: Sattlegger, E.
Silva, RC., Sattlegger, E., & Castilho, BA. (2016). Perturbations in actin dynamics reconfigure protein complexes that modulate GCN2 activity and promote an eIF2 response. Journal of Cell Science. 129(24), 4521-4533
[Journal article]Authored by: Sattlegger, E.
Silva, RC., Dautel, M., Di Genova, BM., Amberg, DC., Castilho, BA., & Sattlegger, E. (2015). The Gcn2 regulator Yih1 interacts with the cyclin dependent kinase Cdc28 and promotes cell cycle progression through G2/M in budding yeast. PLoS ONE. 10(7)
[Journal article]Authored by: Sattlegger, E.
Lee, SJ., Swanson, MJ., & Sattlegger, E. (2015). Gcn1 contacts the small ribosomal protein Rps10, which is required for full activation of the protein kinase Gcn2. Biochemical Journal. 466(3), 547-559
[Journal article]Authored by: Sattlegger, E.
Sattlegger, E., Chernova, TA., Gogoi, NM., Pillai, IV., Chernoff, YO., & Munn, AL. (2014). Yeast studies reveal moonlighting functions of the ancient actin cytoskeleton. IUBMB Life. 66(8), 538-545
[Journal article]Authored by: Sattlegger, E.
Sattlegger, E., Chernova, TA., Gogoi, NM., Pillai, IV., Chernoff, YO., & Munn, AL. (2014). Yeast studies reveal moonlighting functions of the ancient actin cytoskeleton. IUBMB Life.
[Journal article]Authored by: Sattlegger, E.
Castilho, BA., Shanmugam, R., Silva, RC., Ramesh, R., Himme, BM., & Sattlegger, E. (2014). Keeping the eIF2 alpha kinase Gcn2 in check. Biochimica et Biophysica Acta - Molecular Cell Research. 1843(9), 1948-1968
[Journal article]Authored by: Sattlegger, E.
Cridge, AG., Visweswaraiah, J., Ramesh, R., & Sattlegger, E. (2014). Semi-quantitative colony immunoassay for determining and optimizing protein expression in Saccharomyces cerevisiae and Escherichia coli. Analytical Biochemistry. 447(1), 82-89
[Journal article]Authored by: Sattlegger, E.
Wiedemann, M., Lee, SJ., Silva, RC., Visweswaraiah, J., Soppert, J., & Sattlegger, E. (2013). Simultaneous semi-dry electrophoretic transfer of a wide range of differently sized proteins for immunoblotting.. Protocol Exchange. Retrieved from http://www.nature.com/
[Journal article]Authored by: Sattlegger, E.
Reamon-Buettner, SM., Sattlegger, E., Ciribilli, Y., Inga, A., Wessel, A., & Borlak, J. (2013). Transcriptional defect of an inherited NKX2-5 haplotype comprising a SNP, a nonsynonymous and a synonymous mutation, associated with human congenital heart disease. PLoS ONE. 8(12)
[Journal article]Authored by: Sattlegger, E.
Cambiaghi, TD., Pereira, CM., Shanmugam, R., Bolech, M., Wek, RC., Sattlegger, E., . . . Castilho, BA. (2013). Evolutionarily conserved IMPACT impairs various stress responses that require GCN1 for activating the eIF2 kinase GCN2. Biochemical and Biophysical Research Communications.
[Journal article]Authored by: Sattlegger, E.
Visweswaraiah, J., Lee, SJ., Hinnebusch, AG., & Sattlegger, E. (2012). Overexpression of eukaryotic translation elongation factor 3 impairs Gcn2 protein activation. Journal of Biological Chemistry. 287(45), 37757-37768
[Journal article]Authored by: Sattlegger, E.
Waller, T., Lee, SJ., & Sattlegger, E. (2012). Evidence that Yih1 resides in a complex with ribosomes. FEBS Journal.
[Journal article]Authored by: Sattlegger, E.
Visweswaraiah, J., Lageix, S., Castilho, BA., Izotova, L., Kinzy, TG., Hinnebusch, AG., . . . Sattlegger, E. (2011). Evidence that eukaryotic translation elongation factor 1A (eEF1A) binds the Gcn2 protein C terminus and inhibits Gcn2 activity. Journal of Biological Chemistry. 286(42), 36568-36579
[Journal article]Authored by: Sattlegger, E.
Visweswaraiah, J., Dautel, M., & Sattlegger, E. (2011). Generating highly concentrated yeast whole cell extract using low-cost equipment. Protocol Exchange. Retrieved from http://www.nature.com/protocolexchange/protocols/2025
[Journal article]Authored by: Sattlegger, E.
Sattlegger, E., Barbosa, JARG., Moraes, MCS., Martins, RM., Hinnebusch, AG., & Castilho, BA. (2011). Gcn1 and actin binding to Yih1: Implications for activation of the eIF2 kinase GCN2. Journal of Biological Chemistry. 286(12), 10341-10355
[Journal article]Authored by: Sattlegger, E.
Munn, A., & Sattlegger, E. (2009). Yeast studies reveal new roles for an ancient skeleton. Australian Biochemist. 40(2), 9-13 Retrieved from http://www98.griffith.edu.au/dspace/bitstream/handle/10072/31661/59889_1.pdf?sequence=1
[Journal article]Authored by: Sattlegger, E.
Wout, PK., Sattlegger, E., Sullivan, SM., & Maddock, JR. (2009). Saccharomyces cerevisiae Rbg1 protein and its binding partner gir2 interact on polyribosomes with Gcn1. Eukaryotic Cell. 8(7), 1061-1071
[Journal article]Authored by: Sattlegger, E.
Sattlegger, E., & Hinnebusch, AG. (2005). Polyribosome binding by GCN1 is required for full activation of eukaryotic translation initiation factor 2α kinase GCN2 during amino acid starvation. Journal of Biological Chemistry. 280(16), 16514-16521
[Journal article]Authored by: Sattlegger, E.
Pereira, CM., Sattlegger, E., Jiang, HY., Longo, BM., Jaqueta, CB., Hinnebusch, AG., . . . Castilho, BA. (2005). IMPACT, a protein preferentially expressed in the mouse brain, binds GCN1 and inhibits GCN2 activation. Journal of Biological Chemistry. 280(31), 28316-28323
[Journal article]Authored by: Sattlegger, E.
Magazinnik, T., Anand, M., Sattlegger, E., Hinnebusch, AG., & Kinzy, TG. (2005). Interplay between GCN2 and GCN4 expression, translation elongation factor 1 mutations and translational fidelity in yeast. Nucleic Acids Research. 33(14), 4584-4592
[Journal article]Authored by: Sattlegger, E.
Sattlegger, E., Swanson, MJ., Ashcraft, EA., Jennings, JL., Fekete, RA., Link, AJ., . . . Hinnebusch, AG. (2004). YIH1 is an actin-binding protein that inhibits protein kinase GCN2 and impairs general amino acid control when overexpressed. Journal of Biological Chemistry. 279(29), 29952-29962
[Journal article]Authored by: Sattlegger, E.
Alves, VS., Pimenta, DC., Sattlegger, E., & Castilho, BA. (2004). Biophysical characterization of Gir2, a highly acidic protein of Saccharomyces cerevisiae with anomalous electrophoretic behavior. Biochemical and Biophysical Research Communications. 314(1), 229-234
[Journal article]Authored by: Sattlegger, E.
Hinnebusch, AG., Dong, JS., Garcia-Barrio, M., Sattlegger, E., Krishnamoorthy, T., Qiu, HF., . . . Anderson, J. (2000). Translational control in by phosphorylation of initiation factor 2. MOLECULAR BIOLOGY OF THE CELL. 11, 1A-1A
[Journal article]Authored by: Sattlegger, E.
Sattlegger, E., & Hinnebusch, AG. (2000). Separate domains in GCN1 for binding protein kinase GCN2 and ribosomes are required for GCN2 activation in amino acid-starved cells. EMBO Journal. 19(23), 6622-6633
[Journal article]Authored by: Sattlegger, E.
Hoffmann, B., Mösch, HU., Sattlegger, E., Barthelmess, IB., Hinnebusch, A., & Braus, GH. (1999). The WD protein Cpc2p is required for repression of Gcn4 protein activity in yeast in the absence of amino-acid starvation. Molecular Microbiology. 31(3), 807-822
[Journal article]Authored by: Sattlegger, E.
Sattlegger, E., Hinnebusch, AG., & Barthelmess, IB. (1998). cpc-3, the Neurospora crassa homologue of yeast GCN2, encodes a polypeptide with juxtaposed eIF2α kinase and histidyl-tRNA synthetase- related domains required for general amino acid control. Journal of Biological Chemistry. 273(32), 20404-20416
[Journal article]Authored by: Sattlegger, E.
Müller, F., Krüger, D., Sattlegger, E., Hoffmann, B., Ballario, P., Kanaan, M., . . . Barthelmess, IB. (1995). The cpc-2 gene of Neurospora crassa encodes a protein entirely composed of WD-repeat segments that is involved in general amino acid control and female fertility. MGG Molecular & General Genetics. 248(2), 162-173
[Journal article]Authored by: Sattlegger, E.

Thesis

Cheng, Q. (2015). Occurrence of Staphylococcus aureus in a commercial poultry plant and poultry farm. (Master's Thesis)
[Masters Thesis]Contributed to by: Mutukumira, A.Edited by: Mutukumira, A., Sattlegger, E.

Conference

Kruer, M., Padilla-Lopez, S., Helbig, K., Carvill, G., Myers, C., Sebe, J., . . . Mefford, H.Heterozygous de novo Mutations in EEF1A2 Lead to an Epileptic-Dyskinetic Encephalopathy. ANNALS OF NEUROLOGY. (pp. S295 - S296). 0364-5134.
[Conference]Authored by: Sattlegger, E.
Mutukumira, AN., Cheng, Q., & Sattlegger, E. (2015). Using Multilocus Sequence Typing (MLST) method to trace the potential contamination sources of final poultry products by Staphylococcus aureus. In Yes(pp. 1 - 134). , 9th CIGR Section VI International Technical Symposium: Creating value from bio-resources through novel technologies Massey University, Albany, Auckland, New Zealand: CIGR
[Conference Abstract]Authored by: Mutukumira, A., Sattlegger, E.
Sattlegger, E., Jameson, GB., Norris, GE., Burr, N., Loo, TS., Goroncy, A., . . . Harjes, E. (2014). Reconciling Synchotron SAXS Data with NMR Data for a Two-Domain Protein.. (pp. 57 - 58). , The Australian Synchrotron Users Meeting
[Conference Abstract]Authored by: Harjes, E., Jameson, G., Norris, G., Sattlegger, E.
SIlva, RC., Castilho, BA., & Sattlegger, E. (2014). The Gcn2 regulator Yih1 interacts with the cyclin dependent kinase Cdc28 and is involved in the G2/M phase of the budding yeast cell cycle.. (pp. 193 - 193). , EMBL Conference on Protein Synthesis and Translational Control
[Conference Abstract]Authored by: Sattlegger, E.
Jameson, GB., Norris, GE., Burr, N., Loo, TS., Goroncy, A., Sattlegger, E., . . . Harjes, E. (2014). Reconciling synchotron SAXS data with NMR data for a two-domain protein. Poster session presented at the meeting of The Australian Synchrotron Users Meeting 2014. Melbourne, Australia
[Conference Poster]Authored by: Harjes, E., Jameson, G., Norris, G., Sattlegger, E.
SIlva, RC., Castilho, BA., & Sattlegger, E. (2014). The Gcn2 regulator Yih1 interacts with the cyclin dependent kinase Cdc28 and is involved in the G2/M phase of the budding yeast cell cycle. EMBL Conference on Protein Synthesis and Translational Control. Poster session presented at the meeting of European Molecular Biology Laboratory (EMBL), Heidelberg, Germany
[Conference Poster]Authored by: Sattlegger, E.
Jochmann, V., & Sattlegger, E. (2013). Mapping Gcn1 on the ribosome. In conference book(pp. unknown - unknown). , Queenstown Molecular Biology Meeting,
[Conference Abstract]Authored by: Sattlegger, E.
Bolech, M., Joachim, M., & Sattlegger, E. (2013). Identifying potential Yih1 binding proteins required for stimulating protein kinase Gcn2.. (pp. unknwon - unknwon). , Queenstown Molecular Biology Meeting,
[Conference Abstract]Authored by: Sattlegger, E.
Ramesh, R., & Sattlegger, E. (2013). Bimolecular Fluorescence Complementation (BiFC) mediated visualization of protein-protein interactions in vivo in real-time to understand the spatiotemporal regulation of the protein kinase Gcn2.. In conference book(pp. unknwon - unknown). , Queenstown Molecular Biology Meeting
[Conference Abstract]Authored by: Sattlegger, E.
Lee, SJ., Budkevich, T., Cridge, AG., Seberg, A., Hinnebusch, AG., Swanson, MJ., . . . Sattlegger, E. (2013). Evidence that Gcn1 binding to the 40S ribosomal head is essential for fully activating the eIF2α kinase Gcn2.. In conference book(pp. 84 - 84). , Translational Control,
[Conference Abstract]Authored by: Sattlegger, E.
Lee, SJ., Budkevich, T., Cridge, AG., Jochmann, V., Shanmugam, R., Hinnebusch, AG., . . . Sattlegger, E. (2013). Gcn1 binding to the 40S ribosome head region is essential for fully activating the ancient nutrient-sensor-kinase Gcn2.. (pp. 37 - 37). , The New Zealand Microbiological Society (NZMS) Conference,
[Conference Abstract]Authored by: Sattlegger, E.
Ramesh, R., & Sattlegger, E. (2013). Visualizing protein-protein interactions in vivo in real-time to understand the spatiotemporal regulation of the protein kinase Gcn2.. In conference book(pp. 36 - 36). , The New Zealand Microbiological Society (NZMS) Conference
[Conference Abstract]Authored by: Sattlegger, E.
SIlva, RC., Sattlegger, E., & Castilho, BA. (2013). Does the kinase Gcn2 sense the integrity of the actin cytoskeleton in yeas as found in mammals?. (pp. 69 - 69). , Yeast, Products, Discovery and more (YPD2013) conference
[Conference Abstract]Authored by: Sattlegger, E.
Lee, SJ., & Sattlegger, E. (2013). Direct contact between Gcn1 and small tibosomal protein Rps10 is required for full activation of Gcn2 stress sensing kinase.. (pp. 52 - 52). , Yeast, Products, Discovery and more (YPD2013) conference,
[Conference Abstract]Authored by: Sattlegger, E.
Jochmann, V., & Sattlegger, E. (2013). Mapping Gcn1 in the ribosome.. (pp. 47 - 47). , Yeast, Products, Discovery and more (YPD2013) conference
[Conference Abstract]Authored by: Sattlegger, E.
Silva, RC., Castilho, BA., & Sattlegger, E. (2013). Physical interaction between the Gcn2 regulator Yih1 and the cyclin-dependent kinase Cdc28.. (pp. 68 - 68). , Yeast, Products, Discovery and more (YPD2013) conference,
[Conference Abstract]Authored by: Sattlegger, E.
Shanmugam, R., & Sattlegger, E. (2013). Identification of novel Gcn1-binding proteins and their first characterization for their function in Gcn2 regulation.. (pp. 67 - 67). , Yeast, Products, Discovery and more (YPD2013) conference
[Conference Abstract]Authored by: Sattlegger, E.
Ramesh, R., & Sattlegger, E. (2013). Bimolecular fluorescence complementation (BiFC) studies to investigate protein-protein interactions involved in regulating the protein kinase Gcn2.. (pp. 62 - 62). , Yeast, Products, Discovery and more (YPD2013) conference,
[Conference Abstract]Authored by: Sattlegger, E.
Bolech, M., Joachim, M., & Sattlegger, E. (2013). Identifying potential Yih1-binding proteins required for stimulating protein kinase Gcn2.. (pp. 36 - 36). , Yeast, Products, Discovery and more (YPD2013) conference
[Conference Abstract]Authored by: Sattlegger, E.
Cambiaghi, T., Pereira, C., Bolech, M., Shanmugam, R., Sattlegger, E., & Castilho, BA. (2013). Regulation of mammalian Gcn2 by Gcn1 and IMPACT.. In conference book(pp. 117 - 117). , EMBO Protein Synthesis and Translational Control,
[Conference Abstract]Authored by: Sattlegger, E.
Sattlegger, E., Lee, SJ., Budkevich, T., Cridge, AG., Jochmann, V., Seberg, A., . . . Swanson, MJ. (2013). Gcn1 binding to the 40S ribosome head region is essential for fully activating eIF2α kinase Gcn2.. In conference book(pp. 85 - 85). , EMBO Protein Synthesis and Translational Control
[Conference Abstract]Authored by: Sattlegger, E.
Silva, RC., Sattlegger, E., & Castilho, BA. (2013). Does the kinase Gcn2 sense the integrity of the actin cytoskeleton in yeas as found in mammals?. Poster session presented at the meeting of Yeast, Products, Discovery and more (YPD2013) conference. Massey University Auckland
[Conference Poster]Authored by: Sattlegger, E.
Sattlegger, E. (2013). Direct contact between Gcn1 and small tibosomal protein Rps10 is required for full activation of Gcn2 stress sensing kinase.. Poster session presented at the meeting of Yeast, Products, Discovery and more (YPD2013) conference. Massey University Auckland
[Conference Poster]Authored by: Sattlegger, E.
Jochmann, V., & Sattlegger, E. (2013). Mapping Gcn1 in the ribosome.. Poster session presented at the meeting of Yeast, Products, Discovery and more (YPD2013) conference. Massey University Auckland
[Conference Poster]Authored by: Sattlegger, E.
Cambiaghi, T., Pereira, C., Bolech, M., Shanmugam, R., Sattlegger, E., & Castilho, BA. (2013). Regulation of mammalian Gcn2 by Gcn1 and IMPACT.. Poster session presented at the meeting of EMBO Protein Synthesis and Translational Control, EMBL Advanced Training Centre. Heidelberg, Germany
[Conference Poster]Authored by: Sattlegger, E.
Sattlegger, E. (2013). Mapping Gcn1 on the ribosome.. Poster session presented at the meeting of Queenstown Molecular Biology Meeting. Queenstown, New Zealand
[Conference Poster]Authored by: Sattlegger, E.
Bolech, M., Joachim, M., & Sattlegger, E. (2013). Identifying potential Yih1 binding proteins required for stimulating protein kinase Gcn2.. Poster session presented at the meeting of Queenstown Molecular Biology Meeting. Queenstown, New Zealand
[Conference Poster]Authored by: Sattlegger, E.
Ramesh, R., & Sattlegger, E. (2013). Bimolecular Fluorescence Complementation (BiFC) mediated visualization of protein-protein interactions in vivo in real-time to understand the spatiotemporal regulation of the protein kinase Gcn2.. Poster session presented at the meeting of Queenstown Molecular Biology Meeting. Queenstown, New Zealand
[Conference Poster]Authored by: Sattlegger, E.
Lee, ., Lee, SJ., Budkevich, T., Cridge, AG., Jochmann, V., Shanmugam, R., . . . Sattlegger, E. (2013, November). Gcn1 binding to the 40S ribosome head region is essential for fully activating the ancient nutrient-sensor-kinase Gcn2.. Presented at The New Zealand Microbiological Society (NZMS) Conference. Hamilton, New Zealand.
[Conference Oral Presentation]Authored by: Sattlegger, E.
Ramesh, R., & Sattlegger, E. (2013, November). Visualizing protein-protein interactions in vivo in real-time to understand the spatiotemporal regulation of the protein kinase Gcn2.. Presented at The New Zealand Microbiological Society (NZMS) Conference. Hamilton, New Zealand.
[Conference Oral Presentation]Authored by: Sattlegger, E.
Silva, RC., Castilho, BA., & Sattlegger, E. (2013, November). Physical interaction between the Gcn2 regulator Yih1 and the cyclin-dependent kinase Cdc28.. Presented at Yeast, Products, Discovery and more (YPD2013). Massey University Auckland.
[Conference Oral Presentation]Authored by: Sattlegger, E.
Shanmugam, R., & Sattlegger, E. (2013, November). Identification of novel Gcn1-binding proteins and their first characterization for their function in Gcn2 regulation.. Presented at Yeast, Products, Discovery and more (YPD2013). Massey University Auckland.
[Conference Oral Presentation]Authored by: Sattlegger, E.
Ramesh, R., & Sattlegger, E. (2013, November). Bimolecular fluorescence complementation (BiFC) studies to investigate protein-protein interactions involved in regulating the protein kinase Gcn2.. Presented at Yeast, Products, Discovery and more (YPD2013). Massey University Auckland.
[Conference Oral Presentation]Authored by: Sattlegger, E.
Bolech, M., Joachim, M., & Sattlegger, E. (2013, November). Identifying potential Yih1-binding proteins required for stimulating protein kinase Gcn2.. Presented at Yeast, Products, Discovery and more (YPD2013). Massey University Auckland.
[Conference Oral Presentation]Authored by: Sattlegger, E.
Sattlegger, E., Sattlegger, E., Budkevich, R., Cridge, AG., Jochmann, V., Seberg, A., . . . Sattlegger, E. (2013, September). Gcn1 binding to the 40S ribosome head region is essential for fully activating eIF2α kinase Gcn2.. Presented at EMBO Protein Synthesis and Translational Control. EMBL Advanced Training Centre, Heidelberg, Germany.
[Conference Oral Presentation]Authored by: Sattlegger, E.
Dautel, M., Mann, K., Jochmann, V., Ellert, C., & Sattlegger, E. (2012). Identification of Mutations in Actin that affect General Amino Acid Control response.. (pp. 85 - 85). , Translational Control
[Conference Abstract]Authored by: Sattlegger, E.
Sattlegger, E., Lee, SJ., Jochmann, J., Seberg, A., & Swanson, MJ. (2012). Gcn1 binding to the 40S ribosomal head is essential for fully activating the eIF2α kinase Gcn2.. In conference booklet(pp. unknown - unknowm). , New Zealand Microbiological Society (NZMS) Conference
[Conference Abstract]Authored by: Sattlegger, E.
Lee, SJ., Budkevich, T., Cridge, AG., Seberg, A., Hinnebusch, AG., Swanson, MJ., . . . Sattlegger, E. (2012). Evidence that Gcn1 binding to the 40S ribosomal head is essential for fully activating the eIF2α kinase Gcn2. Poster session presented at the meeting of CSHL Translational Control
[Conference Poster]Authored by: Sattlegger, E.
Dautel, M., Mann, K., Jochmann, V., Ellert, C., & Sattlegger, E. (2012). Identification of Mutations in Actin that affect General Amino Acid Control response.. Poster session presented at the meeting of CSHL Translational Control. Cold Spring Harbor, NY, USA
[Conference Poster]Authored by: Sattlegger, E.
Sattlegger, E., Sattlegger, E., Lee, SJ., Jochmann, J., Seberg, A., & Swanson, MJ. (2012, November). Gcn1 binding to the 40S ribosomal head is essential for fully activating the eIF2α kinase Gcn2.. Presented at New Zealand Microbiological Society (NZMS) Conference. Dunedin, New Zealand.
[Conference Oral Presentation]Authored by: Sattlegger, E.
see title/description for more detail, ., & Sattlegger, E. (2011). regular poster presentations by ES. The abstract of each poster was published in Conference booklets: Linkage between translation elongation factors (eEFs) and the kinase Gcn2. Visweswaraiah J, Su J Lee, Lageix S, Castilho BA, Izotova L, Kinzy TG, Hinnebusch AG, and Sattlegger E. 7-11/9/2011 - Gcn1 and actin binding to the central region of Yih1: Implications on Gcn2 activation. Sattlegger E, Moraes MCS, Martins RM, Hinnebusch AG, Barbosa JARG, & Castilho BA. 9-13/9/2009. Poster session presented at the meeting of Conference on Protein Synthesis and Translational Control, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany, 2009, and
[Conference Poster]Authored by: Sattlegger, E.
Visweswaraiah, J., Lee, SJ., Lageix, S., Castilho, BA., Izotova, L., Kinzy, TG., . . . Sattlegger, E. (2011). Linkage between translation elongation factors (eEFs) and the kinase Gcn2. Sep 2011. Poster session presented at the meeting of EMBO Protein Synthesis and Translational Control, EMBL Advanced Training Centre, Heidelberg, Germany
[Conference Poster]Authored by: Sattlegger, E.
Lee, SJ., Seberg, A., Swanson, M., & Sattlegger, E. (2011). Evidence that Gcn1 mediates activation of the nutrient sensor Gcn2 via the ribosomal protein Rps10. Nov 2011. Poster session presented at the meeting of New Zealand Microbiological Society (NZMS) Conference, Convention Centre, Palmerston North, New Zealand
[Conference Poster]Authored by: Sattlegger, E.
Sattlegger, E. (2011, November). Sensing nutient availability in fungi – new insights. Nov 2011. Presented at New Zealand Microbiological Society (NZMS) Conference. Convention Centre, Palmerston North, New Zealand.
[Conference Oral Presentation]Authored by: Sattlegger, E.
Visweswaraiah, J., Lee, SJ., Lageix, S., Castilho, BA., Izotova, L., Kinzy, TG., . . . Sattlegger, E.(2011, September 7). Linkage between translation elongation factors (eEFs) and the kinase Gcn2.. (pp. 282 - 282). , EMBO Protein Synthesis and Translational Control germany: Mera Druck GmbH, Sandhausen
[Conference Abstract]Authored by: Sattlegger, E.
Visweswaraiah, J., Lee, SJ., Lageix, S., Castilho, BA., Izotova, L., Kinzy, TG., . . . Sattlegger, E. (2011). Linkage between translation elongation factors (eEFs) and the kinase Gcn2.. Poster session presented at the meeting of EMBO Protein Synthesis and Translational Control, EMBL Advanced Training Centre, Heidelberg, Germany. see above
[Conference Poster]Authored by: Sattlegger, E.
Sattlegger, E. (2011, August). Revealing novel links between protein synthesis and the nutrient sensor Gcn2.. Presented at QMB Signalling Satellite. Queenstown, New Zealand.
[Conference Oral Presentation]Authored by: Sattlegger, E.
see title/description for more detail, ., & Sattlegger, E. (2010). regular poster presentations by ES, The abstract of each poster was published in Conference booklets: Pinpointing amino acids in Yih1 responsible for affecting GCN1 function. Sattlegger E, Moraes MCS, Martins RM, Hinnebusch AG, Barbosa JARG, and BA Castilho BA. 3-7/9/2010. - Does Yih1 associate with polyribosomes independently of Gcn1? Waller T & Sattlegger E. 3-7/9/2010 - Simultaneous binding of EF1A and the kinase GCN2 to the ribosome? Visweswaraiah J, Hinnebusch AG, and Sattlegger E. 9-13/9/2008 - YIH1, a negative regulator of the eIF2α kinase GCN2, binds actin and GCN1 in overlapping regions. Waller TM, Hinnebusch AG, and Sattlegger E. 6-10/9/2006. Poster session presented at the meeting of Translational Control Conference, Cold Spring Harbor Laboratory, NY, USA, in 2006, 2008, and
[Conference Poster]Authored by: Sattlegger, E.
Dautel, M., Mann, K., & Sattlegger, E.(2010, November 30). Actin-YIH1 interaction - does the cytoskeleton talk to the kinase regulator?. In New Zealand Microbiological Society and New Zealand Society for Biochemistry and Molecular Biology, New Zealand Microbiological Society and New Zealand Society for Biochemistry and Molecular Biology: New Zealand Microbiological Society, New Zealand Society for Biochemistry and Molecular Biology
[Conference Abstract]Authored by: Sattlegger, E.
Visweswaraiah, J., Hinnebusch, A., & Sattlegger, E.(2010, November 30). Sensing starvation and protein synthesis - can both happen on the ribosome simultaneously?. , NZMS and NZSBMB Joint Meeting
[Conference Abstract]Authored by: Sattlegger, E.
Dautel, M., Mann, K., & Sattlegger, E. (2010, November). Actin-YIH1 Interaction - does the cytoskeleton talk to the kinase regulator. Presented at NZMS and NZSBMB Joint Meeting. The University of Auckland, New Zealand.
[Conference Oral Presentation]Authored by: Sattlegger, E.
Dautel, M., Mann, K., & Sattlegger, E.(2010, November 30). Actin-YIH1 interaction - does the cytoskeleton talk to the kinase regulator?. , NZMS and NZSBMB Joint Meeting
[Conference Abstract]Authored by: Sattlegger, E.
Waller, T., & Sattlegger, E.(2010, September 13). Does Yih1 associate with polyribosomes independently of GCN1?. (pp. 248). , Translational Control: CSH
[Conference Abstract]Authored by: Sattlegger, E.
Sattlegger, E.(2010, November 29). Regulating the ancient food sensor Gcn2. , Symposium on Fungal and Yeast Cell Biology
[Conference Abstract]Authored by: Sattlegger, E.
Waller, T., & Sattlegger, E. (2010). Does Yih1 associate with polyribosomes independently of Gcn1?. Poster session presented at the meeting of Cold Spring Harbor, NY, USA. Cold Spring Harbour
[Conference Poster]Authored by: Sattlegger, E.
Sattlegger, E., Moraes, MCS., Martins, RM., Hinnebusch, AG., Barbosa, JARG., & Castilho, BA. (2010). Pinpointing amino acids in Yih1 responsible for affecting Gcn1 function. . Cold Spring Harbor, NY, USA
[Conference Poster]Authored by: Sattlegger, E.
Sattlegger, E. (2010, June). Yeast molecular biology. Presented at Auckland Fungal Biology Group meeting. Auckland University.
[Conference Oral Presentation]Authored by: Sattlegger, E.
Sattlegger, E. (2010, November). Regulating the ancient food sensor Gcn2. Presented at Symposium on Fungal and Yeast Cell Biology. Massey University, Auckland, New Zealand.
[Conference Oral Presentation]Authored by: Sattlegger, E.
Visweswaraiah, J., Hinnebusch, AG., & Sattlegger, E. (2010, November). Sensing starvation and protein synthesis: Can both happen on the ribosome simultaneously?. Presented at Small things, Big Ideas. Auckland, New Zealand.
[Conference Oral Presentation]Authored by: Sattlegger, E.
Sattlegger, E., & Waller, T.(2010, September 3). Does Yih1 associate with polyribosomes independently of Gcn1.
[Conference Abstract]Authored by: Sattlegger, E.
Sattlegger, E., Moraes, MCS., Martins, RM., Hinnebusch, AG., Barbosa, JARG., & Castilho, BA.(2010, September 13). Pinpointing amino acids in Yih1 responsible for affecting GCN1 function. (pp. 249).
[Conference Abstract]Authored by: Sattlegger, E.
Sattlegger, E., & Dautel M, . (2010, November). Shedding light on the link between the actin cytoskeleton and stress response.. Presented at Small things, Big Ideas. Auckland, New Zealand.
[Conference Oral Presentation]Authored by: Sattlegger, E.
Barbosa, J., Moraes, M., Martins, R., Castilho, B., Sattlegger, E., & Hinnebusch, A.Gcn1 and actin binding to the central region of Yih1: Implications on Gcn2 activation. (pp. 228 - 228). : EMBO Conference Series on Protein Synthesis and Translational Control
[Conference Paper in Published Proceedings]Authored by: Sattlegger, E.
Sattlegger, E., Moraes, MCS., Martins, RM., Hinnebusch, AG., Barbosa, JARG., & Castilho, B.(2009, December 6). Memory versus starvation what can yeast tell us about Yih1 mediated regulation of protein kinase Gcn2?. , Combio 2009
[Conference Abstract]Authored by: Sattlegger, E.
Cridge, A., Lee, S., & Sattlegger, E.(2009, December 6). Amino acid starvation response in Saccharomyces cerevisiae: Molecular mechanisms involving protein switches and ribosomes. , Combio Christchurch Convention Centre
[Conference Abstract]Authored by: Sattlegger, E.
Sattlegger, E., Moraes, MCS., Martins, RM., Hinnebusch, AG., Barbosa, JARG., & Castilho, BA. (2009). Memory versus Starvation. What can yeast tell us about Yih1 mediated regulation of protein kinase Gcn2?. Poster session presented at the meeting of ComBio Conference, Christchurch, New Zealand
[Conference Poster]Authored by: Sattlegger, E.
Sattlegger, E. (2009, February). Using Saccharomyces for basic research, biomedical research, and biotechnology. Presented at Inaugural New Zealand Yeast Group Meeting. Bethel’s beach, University of Auckland.
[Conference Oral Presentation]Authored by: Sattlegger, E.
Sattlegger, E., Moraes, MCS., Martins, RM., Hinnebusch, AG., Barbosa, JARG., & Castilho, BA. (2009, December). Starvation versus memory: What can yeast tell us about Yih1-mediated regualtion of protein kinase Gcn2?. Presented at Yeast: Products and Discovery. Charles Hawker Conference Centre, The University of Adelaide, Waite Campus, Australia.
[Conference Oral Presentation]Authored by: Sattlegger, E.
Sattlegger, E., Cridge, A., & Lee, SJ. (2009, December). Amino acid starvation response in Saccharomyces cerevisiae: Molecular mechanisms involving protein switches and ribosomes. Presented at ComBio Conference. Christchurch, New Zealand.
[Conference Oral Presentation]Authored by: Sattlegger, E.
Sattlegger, E., Moraes, MCS., Martins, RM., Hinnebusch, AG., Barbosa, JARG., & JARG, B.(2009, September 14). Gcn1 and actin binding to the central region of Yih1: Implications on Gcn2 activation. , EMBL Conference on Protein Synthesis and Translational Control
[Conference Abstract]Authored by: Sattlegger, E.
Sattlegger, E., Moraes, MCS., Martins, RM., Hinnebusch, AG., Barbosa, JARG., & Castilho, BA.(2009, December 6). Memory versus Starvation. What can yeast tell us about Yih1 mediated regulation of protein kinase Gcn2?. , ComBio Conference
[Conference Abstract]Authored by: Sattlegger, E.
Sattlegger, E., Moraes, MC., Martins, RM., Hinnebusch, H., Barbosa, JA., & Castilho, BA. (2009). Starvation versus memory: What can yeast tell us about Yih1-medicated regulation of protein kinase Gcn2?. In Yeast: Products and Discovery(pp. 1 - 20). : University of Adelaide
[Conference Abstract]Authored by: Sattlegger, E.
Visweswaraiah, J., & Sattlegger, E.Exclusive ribosome occupancy of EF3 and GCN1?. (pp. 15 - 15). : Biological Sciences Student Research Symposium 2008
[Conference Paper in Published Proceedings]Authored by: Sattlegger, E.
Dautel, M., & Sattlegger, E.(2008, December 11). IMPACT, actin, GCN2: Hunger management not only in yeast. , Biological Sciences Student Research Symposium 2008
[Conference Abstract]Authored by: Sattlegger, E.
Macfarlane, R., & Sattlegger, E.(2008, December 11). Optimizing expression and purification of selected general amino acid control (GAAC) proteins. , Biological Sciences Student Research Symposium 2008
[Conference Abstract]Authored by: Sattlegger, E.
Sattlegger, E. (2008). Gcn1 and actin binding to the central region of Yih1: Implications on Gcn2 activation. Poster session presented at the meeting of EMBO Conference on Protein Synthesis and Translational Control, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany. Heidelberg, Germany
[Conference Poster]Authored by: Sattlegger, E.
Sattlegger, E., & Dautel, M. (2008, December). IMPACT, actin, GCN2: Hunger management not only in yeast. Presented at Student symposium. Massey University, Auckland.
[Conference Oral Presentation]Authored by: Sattlegger, E.
Sattlegger, E., & Visweswaraiah, J. (2008, December). Exclusive Ribosome Occupancy of EF3 and GCN1?. Presented at Student symposium. Massey University, Auckland.
[Conference Oral Presentation]Authored by: Sattlegger, E.
Sattlegger, E., & MacFarlane, R. (2008, December). Optimizing expression and purification of selected General Amino Acid Control (GAAC) proteins. Presented at Student symposium. Massey University, Auckland.
[Conference Oral Presentation]Authored by: Sattlegger, E.
Visweswaraiah, J., Hinnebusch, AG., & Sattlegger, E. (2008). Simultaneous binding of EF1A and the kinase GCN2 to the ribosome?. Poster session presented at the meeting of Translational Control Conference, Cold Spring Harbor, NY, USA. New York, NY
[Conference Poster]Authored by: Sattlegger, E.
Visweswaraiah, J., Hinnebusch, AG., & Sattlegger, E. (2008). Simultaneous binding of EF1A and the kinase GCN2 to the ribosome?. In Proceedings of the 2008 Meeting on Translational Control(pp. 319). : CSH
[Conference Abstract]Authored by: Sattlegger, E.
Dautel, M., Mann, KJ., & Sattlegger, E.(2008). Using yeast to unravel the link between actin, GCN2-signalling, and the brain protein IMPACT. . Queenstown, NZ
[Conference Other]Authored by: Sattlegger, E.
Dautel, M., Mann, KJ., & Sattlegger, E. (2008). Using yeast to unravel the link between actin, GCN2-signalling, and the brain protein IMPACT. In Queenstown Molecular Biology Meetings: 18th Annual Queenstown Molecular Biology Meeting(pp. 138). : QMB
[Conference Abstract]Authored by: Sattlegger, E.
Dautel, M., Mann, KJ., & Sattlegger, E. (2008). Using yeast to unravel the link between actin, GCN2-signalling, and the brain protein IMPACT. Poster session presented at the meeting of Queenstown Molecular Biology Meetings: 3rd New Zealand Proteins Meeting. Queenstown, NZ
[Conference Poster]Authored by: Sattlegger, E.
Dautel, M., Mann, KJ., & Sattlegger, E. (2008). Using yeast to unravel the link between actin, GCN2-signalling, and the brain protein IMPACT. In Queenstown Molecular Biology Meetings: 3rd New Zealand Proteins Meeting(pp. 234). : QMB
[Conference Abstract]Authored by: Sattlegger, E.
Dautel, M., Mann, KJ., & Sattlegger, E. (2008). Using yeast to unravel the link between actin, GCN2-signalling, and the brain protein IMPACT. Poster session presented at the meeting of Queenstown Molecular Biology Meetings: 2nd Queenstown Signal Transduction Meetings. Queenstown, NZ
[Conference Poster]Authored by: Sattlegger, E.
Mann, K., & Sattlegger, E. (2007). Does actin control GCN2 kinase-activity via YIH1?. (pp. S63 - S63). : XXIII International Conference on Yeast Genetic and Molecular Biology
[Conference Paper in Published Proceedings]Authored by: Sattlegger, E.
Mann, K., & Sattlegger, E. (2007). Does actin control GCN2 kinase-activity via YIH1?. (pp. S63 - S63). : XXIII International Conference on Yeast Genetic and Molecular Biology
[Conference Paper in Published Proceedings]Authored by: Sattlegger, E.
Sattlegger, E., & Visweswaraiah, J. (2007). Translation machinery and stress-sensing complex: how do they get along on the ribosome?. Presented at student symposium. Massey University Palmerston North.
[Conference Oral Presentation]Authored by: Sattlegger, E.
Dautel, M., Mann, KJ., & Sattlegger, E. (2007). Actin-YIH1 interaction - Does the cytoskeleton talk to the kinase regulator?. Poster session presented at the meeting of Joint New Zealand Microbiological Society (NZMS)-New Zealand Society for Biochemistry and Molecular Biology (NZSBMB) Annual Conference. Victoria University of Wellington, Wellington, New Zealand
[Conference Poster]Authored by: Sattlegger, E.
Dautel, M., Mann, KJ., & Sattlegger, E. (2007). Actin-YIH1 interaction - Does the cytoskeleton talk to the kinase regulator?. In Joint New Zealand Microbiological Society (NZMS)-New Zealand Society for Biochemistry and Molecular Biology (NZSBMB) Annual Conference(pp. 105). : NZMS / NZSBMB
[Conference Abstract]Authored by: Sattlegger, E.
Visweswaraiah, J., Hinnebusch, AG., & Sattlegger, E. (2007). Translation machinery and stress-sensing complex: How do they get along on the ribosome?. In Joint New Zealand Microbiological Society (NZMS)-New Zealand Society for Biochemistry and Molecular Biology (NZSBMB) Annual Conference(pp. 93). : NZMS / NZSBMB
[Conference Abstract]Authored by: Sattlegger, E.
Visweswaraiah, J., Hinnebusch, AG., & Sattlegger, E. (2007, November). Translation machinery and stress-sensing complex: How do they get along on the ribosome?. Presented at Joint New Zealand Microbiological Society (NZMS)-New Zealand Society for Biochemistry and Molecular Biology (NZSBMB) Annual Conference. Victoria University of Wellington, Wellington, NZ.
[Conference Oral Presentation]Authored by: Sattlegger, E.
Sattlegger, E. (2007, July). Does actin control GCN2 kinase-activity via YIH1?. Presented at 23rd International Conference on Yeast Genetics and Molecular Biology. Melbourne, VIC.
[Conference Oral Presentation]Authored by: Sattlegger, E.
Visweswaraiah, J., & Sattlegger, E. (2007, July). How does GCN2 capture the starvation signal?. Presented at Crosstalk / New Zealand Society for Biochemistry and Molecular Biology Signal Transduction Symposium. University of Auckland, Auckland, NZ.
[Conference Oral Presentation]Authored by: Sattlegger, E.
Visweswaraiah, J., & Sattlegger, E. (2007). How does GCN2 capture the starvation signal?. In Crosstalk / New Zealand Society for Biochemistry and Molecular Biology Signal Transduction Symposium(pp. 17). : Crosstalk / New Zealand Society for Biochemistry and Molecular Biology
[Conference Abstract]Authored by: Sattlegger, E.
Dautel, M., Mann, KJ., & Sattlegger, E. (2007). Is actin controlling the GCN2 signalling pathway?. In Crosstalk / New Zealand Society for Biochemistry and Molecular Biology Signal Transduction Symposium(pp. 19). : Crosstalk / New Zealand Society for Biochemistry and Molecular Biology
[Conference Abstract]Authored by: Sattlegger, E.
Dautel, M., Mann, KJ., & Sattlegger, E. (2007). Is actin controlling the GCN2 signalling pathway?. Poster session presented at the meeting of Crosstalk / New Zealand Society for Biochemistry and Molecular Biology Signal Transduction Symposium. University of Auckland, Auckland, NZ
[Conference Poster]Authored by: Sattlegger, E.
Mann, KJ., & Sattlegger, E. (2007). Does actin control GCN2 kinase-activity via YIH1?. In 23rd International Conference on Yeast Genetics and Molecular Biology(pp. S63). : John Wiley and Sons [Yeast, 24(S1)]
[Conference Abstract]Authored by: Sattlegger, E.
Mann, KJ., & Sattlegger, E. (2007). Does actin control GCN2 kinase-activity via YIH1?. Poster session presented at the meeting of 23rd International Conference on Yeast Genetics and Molecular Biology. Melbourne, VIC
[Conference Poster]Authored by: Sattlegger, E.
Waller, TM., Hinnebusch, AG., & Sattlegger, E. (2006). How do actin and YIH1 regulate the activity of GCN2, a kinase essential for overcoming amino acid starvation?. In 16th Annual Queenstown Molecular Biology Meeting(pp. 10). : QMB Society
[Conference Abstract]Authored by: Sattlegger, E.
Waller, TM., Hinnebusch, AG., & Sattlegger, E. (2006). YIH1, a negative regulator of the eIF2α kinase GCN2, binds actin and GCN1 in overlapping regions. Poster session presented at the meeting of Translational Control. Cold Spring Harbor , NY
[Conference Poster]Authored by: Sattlegger, E.
Waller, TM., Hinnebusch, AG., & Sattlegger, E. (2006). YIH1, a negative regulator of the eIF2α kinase GCN2, binds actin and GCN1 in overlapping regions. In Translational Control(pp. 314). : Cold Spring Harbor Laboratory
[Conference Abstract]Authored by: Sattlegger, E.
Sattlegger, E. (2006, August). How do actin and YIH1 regulate the activity of GCN2, a kinase essential for overcoming amino acid starvation?. Presented at 16th Annual Queenstown Molecular Biology Meeting. Queenstown, NZ.
[Conference Oral Presentation]Authored by: Sattlegger, E.
Sattlegger, E., & Hinnebusch, AG. (2005). Signalling amino acid starvation - studies at the molecular level. (pp. 43). , 2nd Barossa meeting - Signalling Networks: Barossa Science Amongst the Vines Institute of Medical and Veterinary Science: Division of Human Immunology
[Conference Abstract]Authored by: Sattlegger, E.
Sattlegger, E., & Hinnebusch, AG. (2005, November). Signalling amino acid starvation: Studies at a molecular level. Presented at 2nd Barossa Meeting - Signalling Networks: Barossa Science Amongst the Vines. Barossa Valley, SA.
[Conference Oral Presentation]Authored by: Sattlegger, E.
Sattlegger, E., & Hinnebusch, AG. (2005). Polysome binding by GCN1 is required for full activation of eIF2α kinase GCN2 in amino acid limitation. (pp. 231). , The European Molecular Biology Organization Conference on Protein Synthesis and Translational Control Sandhausen, Germany: MeraDruck GmbH, Sandhausen
[Conference Abstract]Authored by: Sattlegger, E.
Sattlegger, E., & Hinnebusch, AG. (2005). Polyribosome binding by GCN1 is required for full activation of eIF2α kinase GCN2 in amino acid limitation. Poster session presented at the meeting of The European Molecular Biology Organization Conference on Protein Synthesis and Translational Control. Heidelberg, Germany
[Conference Poster]Authored by: Sattlegger, E.
Sattlegger, E., & Hinnebusch, AG. (2004). Activation of eIF2α kinase GCN2 requires GCN1-ribosome interaction and attendant modulation of A-site function by GCN1. (pp. 64). , Yeast Genetics and Molecular Biology Meeting Bethesda, Maryland, WA: The Genetics Society of America
[Conference Abstract]Authored by: Sattlegger, E.
Sattlegger, E., & Hinnebusch, AG. (2004, July). Activation of eIF2α kinase GCN2 requires GCN1-ribosome interaction and attendant modulation of A-site function by GCN1. Presented at Yeast Genetics and Molecular Biology Meeting. University of Washington, Seattle, WA.
[Conference Oral Presentation]Authored by: Sattlegger, E.
Sattlegger, E., & Hinnebusch, AG. (2004). Evidence that binding to polysomes and modulating A-site function by GCN1 is required for activating eIF2α kinase GCN2. (pp. Unpaged). , Baltimore/Washington Protein Synthesis Meeting Baltimore, MD: Johns Hopkins University School of Medicine
[Conference Abstract]Authored by: Sattlegger, E.
Sattlegger, E., & Hinnebusch, AG. (2004, April). Evidence that binding to polysomes and modulating A-site function by GCN1 is required for activating eIF2α kinase GCN2. Presented at Baltimore/Washington Protein Synthesis Meeting. Baltimore, MD.
[Conference Oral Presentation]Authored by: Sattlegger, E.
Sattlegger, E., & Hinnebusch, AG. (2004). GCN1 binding to translating ribosomes is essential for activation of the eIF2α kinase GCN2. In Translational Control: Abstract Papers Presented at the 2004 Meeting on Translational Control(pp. 322 - 322). , Translational Control Meeting Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press
[Conference Abstract]Authored by: Sattlegger, E.
Sattlegger, E., & Hinnebusch, AG. (2004). GCN1 binding to translating ribosomes is essential for activation of the eIF2α kinase GCN2. Poster session presented at the meeting of Translational Control Meeting 2004. Cold Spring Harbor, NY
[Conference Poster]Authored by: Sattlegger, E.
Pereira, CM., Sattlegger, E., Longo, BM., Jaqueta, CB., Hinnebusch, AG., Mello, LE., . . . Castilho, BA. (2004). IMPACT, a protein preferentially expressed in the mouse brain, binds GCN1, and its abundance is inversely correlated with eIF2α phosphorylation levels. In Translational Control Meeting(pp. 299). , Translational Control Meeting 2004 Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press
[Conference Abstract]Authored by: Sattlegger, E.
Pereira, CM., Sattlegger, E., Longo, BM., Jaqueta, CB., Hinnebusch, AG., Mello, LE., . . . Castilho, BA. (2004). IMPACT, a protein preferentially expressed in the mouse brain, binds GCN1, and its abundance is inversely correlated with eIF2α phosphorylation levels. Poster session presented at the meeting of Translational Control Meeting 2004. Cold Spring Harbor, NY
[Conference Poster]Authored by: Sattlegger, E.
Sattlegger, E., & Hinnebusch, AG. (2004). Activation of eIF2α kinase GCN2 requires GCN1-ribosome interaction and attendant modulation of A-site function by GCN1. Poster session presented at the meeting of National Institutes of Health Research Festival. Bethesda, MD
[Conference Poster]Authored by: Sattlegger, E.
Sattlegger, E., Swanson, MJ., Ashcraft, EA., Jennings, JL., Link, AJ., & Hinnebusch, AG. (2003). YIH1 is an Actin-binding protein that negatively regulates the eIF2α-kinase GCN2 when Actin is sparse. Poster session presented at the meeting of 2003 National Institutes of Health Research Festival. Bethesda, MD
[Conference Poster]Authored by: Sattlegger, E.
Sattlegger, E., Valente, L., Andersen, G., Kinzy, TG., & Nierhaus, K. (2002). Elucidating the function of the GCN1/20 complex on the ribosome. Poster session presented at the meeting of Max Planck Institute for Molecular Genetics: Day of Scientific Exchange. Berlin, Germany
[Conference Poster]Authored by: Sattlegger, E.
Sattlegger, E., Swanson, MJ., Link, AJ., & Hinnebusch, AG. (2002). Role of YIH1 in negative regulation of eIF2α kinase GCN2. Poster session presented at the meeting of Translational Control Meeting. Cold Spring Harbor, NY
[Conference Poster]Authored by: Sattlegger, E.
Sattlegger, E., Swanson, MJ., Link, AJ., & Hinnebusch, AG. (2002). Role of YIH1 in negative regulation of eIF2α kinase GCN2. (pp. 308 - 308). , Translational Control Meeting Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press
[Conference Abstract]Authored by: Sattlegger, E.
Sattlegger, E., Swanson, MJ., Link, AJ., & Hinnebusch, AG. (2002). Negative regulation of general amino acid control by actin and YIH1, the yeast homolog of mammalian IMPACT. Poster session presented at the meeting of National Institutes of Health Research Festival. Bethesda, MD
[Conference Poster]Authored by: Sattlegger, E.
Dong, J., Qiu, H., Sattlegger, E., Garcia Barrio, M., Francklyn, CS., & Hinnebusch, AG. (2001, October). A domain related to histidyl-tRNA synthetase in GCN2 mediates kinase activation by uncharged tRNA by an autoinhibitory mechanism. Presented at 4th West Coast Meeting on mRNA Stability and Translation. Seattle, WA.
[Conference Oral Presentation]Authored by: Sattlegger, E.
Sattlegger, E., Swanson, MJ., & Hinnebusch, AG. (2001). Binding of GCN1 near the ribosomal A-site and to the N-terminus of GCN2 is required for activation of the kinase GCN2 in amino acid starved cells. In 66th Cold Spring Harbor Symposium on Quantitative Biology: The Ribosome(pp. 132). , 66th Cold Spring Harbor Symposium on Quantitative Biology: The Ribosome Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press
[Conference Abstract]Authored by: Sattlegger, E.
Sattlegger, E., Swanson, MJ., & Hinnebusch, AG. (2001). Binding of GCN1 near the ribosomal A-site and to the N-terminus of GCN2 is required for activation of the kinase GCN2 in amino acid starved cells. Poster session presented at the meeting of 66th Cold Spring Harbor Symposium on Quantitative Biology: The Ribosome. Cold Spring Harbor, NY
[Conference Poster]Authored by: Sattlegger, E.
Sattlegger, E., Swanson, M., & Hinnebusch, A. (2001). Binding of GCN1 near the ribosomal A-site and to the N-terminus of GCN2 is required for activation of the kinase GCN2 in amino acid starved cells.. In YEAST Vol. 18 (pp. S193 - S193). : JOHN WILEY & SONS LTD
[Conference Abstract]Authored by: Sattlegger, E.
Sattlegger, E., Swanson, MJ., & Hinnebusch, AG. (2001). Binding of GCN1 near the ribosomal A-site and to the N-terminus of GCN2 is required for activation of the kinase GCN2 in amino acid starved cells. Poster session presented at the meeting of 20th International Conference on Yeast Genetics and Molecular Biology. Prague, Czech Republic
[Conference Poster]Authored by: Sattlegger, E.
Dong, J., Qiu, H., Sattlegger, E., Garcia Barrio, M., Francklyn, CS., & Hinnebusch, AG. (2001). A domain related to histidyl-tRNA synthetase in GCN2 mediates kinase activation by uncharged tRNA by an autoinhibitory mechanism. (pp. 11). , 4th West Coast Meeting on mRNA Stability and Translation Seattle, WA: University of Washington
[Conference Abstract]Authored by: Sattlegger, E.
Sattlegger, E., Garcia Barrio, M., Dong, J., Ufano, S., & Hinnebusch, AG. (2000). Binding of the GCN1/GCN20 complex to the N-terminus of GCN2 is required for the eIF2α kinase activity of GCN2 in amino acid starved cells. (pp. 285). , Meeting on Translational Control Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press
[Conference Abstract]Authored by: Sattlegger, E.
Sattlegger, E., Garcia Barrio, M., Dong, J., Ufano, S., & Hinnebusch, AG. (2000). Binding of the GCN1/GCN20 complex to the N-terminus of GCN2 is required for the eIF2α kinase activity of GCN2 in amino acid starved cells. Poster session presented at the meeting of Meeting on Translational Control. Cold Spring Harbor, NY
[Conference Poster]Authored by: Sattlegger, E.
Sattlegger, E., & Hinnebusch, AG. (2000). Separate domains in GCN1 for binding protein kinase GCN2 and ribosomes are required for GCN2 activation in amino acid starved cells. Poster session presented at the meeting of National Institutes of Health Research Festival 2000. Bethesda, MD
[Conference Poster]Authored by: Sattlegger, E.
Hinnebusch, AG., Dong, J., Garcia Barrio, M., Sattlegger, E., Krishnamoorthy, T., Qiu, H., . . . Anderson, J. (2000, December). Mechanism of translational control in yeast by phosphorylation of initiation factor 2. Presented at American Society for Cell Biology 40th Annual Meeting. San Francisco, CA.
[Conference Oral Presentation]Authored by: Sattlegger, E.
Sattlegger, E.Revealing novel links between protein synthesis and the nutrient sensor Gcn2. 29 Aug 2011.
[Conference Oral Presentation]Authored by: Sattlegger, E.

Other

Sattlegger, E. (2015, April). In search for novel proteins that keep in check Gcn2, an enzyme implicated in many biological functions and diseases/disorders. (University of Sao Paulo, Brazil).
[Oral Presentation]Authored by: Sattlegger, E.
Sattlegger, E. (2014, August). Towards understanding how cells keep in check Gcn2, a protein kinase involved in many crucial biological functions and implicated in diseases/disorders. (Emory Unversity, Altanta, GA, USA, 20/8/2014 , Georgia Institute of Technology, Atlanta, GA, USA, 18/8/2014).
[Oral Presentation]Authored by: Sattlegger, E.
Sattlegger, E. (2014, August). Towards understanding how cells keep in check Gcn2, a protein kinase involved in many crucial biological functions and implicated in diseases/disorders..
[Oral Presentation]Authored by: Sattlegger, E.
Sattlegger, E. (2014, June). The protein kinase Gcn2. An ancient nutrient sensor that inadvertently supports cancer cell growth.. Presented at The University of Auckland, Faculty of Medical and Health Sciences, Auckland.
[Oral Presentation]Authored by: Sattlegger, E.
Sattlegger, E. (2013, November). Using baker’s yeast as guinea pig for understanding mammalian/human signal transduction pathways.. Presented at Massey University Albany, New Zealand.
[Oral Presentation]Authored by: Sattlegger, E.
Sattlegger, E. (2013, August). Mapping Gcn1 on the ribosome, using genetic methods.. Presented at Charité Medical University, Berlin, Germany.
[Oral Presentation]Authored by: Sattlegger, E.
Sattlegger, E. (2013, August). Towards understanding the regulatory network controlling the protein kinase Gcn2 (University of Nijmegen, The Netherlands).
[Oral Presentation]Authored by: Sattlegger, E.
Sattlegger, E. (2012, September). Results on Gcn2 regulators (National Institutes of Health (NIH), USA).
[Oral Presentation]Authored by: Sattlegger, E.
Sattlegger, E. (2012, August). Using yeast to understand how our cells sense and overcome starvation for amino acids..
[Oral Presentation]Authored by: Sattlegger, E.
Sattlegger, E. (2010). regular invitations to give oral presentation on new research findings: Cytoskeletal effects on sensing amino acid starvation: when amino acid hunger is actin up. 20 Sep 2008 - Interactome studies on the GAAC pathway. 24 Sep 2010 - Biology department, University of Nebraska, Omaha, NE, USA.. Presented at Biology department, University of Nebraska, Omaha, NE, USA. 2008 and.
[Oral Presentation]Authored by: Sattlegger, E.
Sattlegger, E. (2010, June). Yeast molecular biology.
[Oral Presentation]Authored by: Sattlegger, E.
Sattlegger, E. (2010, September). Interactome studies on the GAAC pathway, Sep 24 2010. Presented at University of Nebraska, Omaha, NE, USA.
[Oral Presentation]Authored by: Sattlegger, E.
Sattlegger, E. (2009, November). Research - Sattlegger group. In Biosciences team of the Australian Wine Research Institute (AWRI).
[Oral Presentation]Authored by: Sattlegger, E.
Sattlegger, E. (2009, April). Gcn proteins are important for (Eukaryotic) cells. Presented at Ludwig Maximilian University, Munich, Germany.
[Oral Presentation]Authored by: Sattlegger, E.
Sattlegger, E. (2009, November). Protein synthesis and sensing starvation for amino acids - What is the connection?. Presented at Adelaide Wine Research Institute (AWRI), Australia.
[Oral Presentation]Authored by: Sattlegger, E.
Sattlegger, E. (2008, March). Das Enträtseln von wichtigen biologischen Prozessen - Wie kann Bäkerhefe uns dabei helfen? [Unravelling the molecular mechanism of important biological processes – How can baker’s yeast help us?].
[Oral Presentation]Authored by: Sattlegger, E.
Sattlegger, E. (2008, March). Unravelling the molecular mechanism of important biological processes- How baker's yeast help us?. In Hamburg University of Applied Sciences. Presented at Hamburg, Germany.
[Oral Presentation]Authored by: Sattlegger, E.
Sattlegger, E. (2008, May). Studying the function of YIH1, the yeast homologue of the brain protein impact. In Universita Degli Studi di Trento. Presented at Trento, Italy.
[Oral Presentation]Authored by: Sattlegger, E.
Sattlegger, E. (2007). Hungry (f)or memory? Unravelling molecular mechanisms involved in regulating the protein kinase GCN2. Presented at University of Auckland, Auckland, NZ.
[Oral Presentation]Authored by: Sattlegger, E.
Sattlegger, E. (2007, May). Die Hefe ist eine kleine Pflanze" (Yeast is a little plant). In Institute of Botany Seminar.
[Oral Presentation]Authored by: Sattlegger, E.
Sattlegger, E. (2006, September). How do we know that we are hungry? Sensing amino acid starvation. What is the molecular mechanism? And more implications .... In Department of Biology. Presented at University of Nebraska, Omaha, NE.
[Oral Presentation]Authored by: Sattlegger, E.
Sattlegger, E. (2006). What can baker's yeast tell us about neurons?. Presented at Auckland, New Zealand.
[Oral Presentation]Authored by: Sattlegger, E.
Sattlegger, E. (2006). How do we know we are hungry?: Unravelling molecular mechanisms involved in signalling amino acid starvation. Presented at University of Auckland, Auckland, NZ.
[Oral Presentation]Authored by: Sattlegger, E.
Sattlegger, E. (2005, September). Sensing amino acid starvation. What is the molecular mechanism? And more implications.... : Max Planck Institute for Molecular Genetics.
[Oral Presentation]Authored by: Sattlegger, E.
Sattlegger, E. (2005, September). Sensing amino acid starvation. What is the molecular mechanism? How does the cell respond adequately? More implications.... : Georg-August University.
[Oral Presentation]Authored by: Sattlegger, E.
Sattlegger, E. (2004, February). Elucidating the signaling of amino acid starvation in Eukaryotes. : Max Planck Institute for Molecular Genetics.
[Oral Presentation]Authored by: Sattlegger, E.
Sattlegger, E. (2003, November). Elucidating the function of the ribosome in sensing amino acid starvation in Eukaryotes. : 8th Workshop on Experimental Strategies for Ribosomal Research.
[Oral Presentation]Authored by: Sattlegger, E.
Sattlegger, E. (2001, November). Stringent control in yeast. : Max Planck Institute for Molecular Genetics.
[Oral Presentation]Authored by: Sattlegger, E.
Sattlegger, E. (2001, May). Separate domains in GCN1 for binding protein kinase GCN2 and ribosomes are required for GCN2 activation in amino acid-starved cells. : LMGR-LGRD-SDRRM Joint Seminar.
[Oral Presentation]Authored by: Sattlegger, E.
Sattlegger, E.regular invitations to give oral presentation on research conducted by students from Hamburg University who worked in the Sattlegger lab as interns: Ein Einblick in die Forschung eines wichtigen Signaltransduktionsweges. [Insights into the research on an important signal transduction pathway]. 22 Sep 2011 - Unravelling the molecular mechanism of important biological processes- How can baker's yeast help us? 08 Mar 2008 - University of Applied Sciences, Hamburg, Germany.. Presented at University of Applied Sciences, Hamburg, Germany..
[Oral Presentation]Authored by: Sattlegger, E.
Sattlegger, E.Newest results on Gcn1-ribosome interaction. 19/20 Sept 2011. Presented at Charite, Berlin, Germany.
[Oral Presentation]Authored by: Sattlegger, E.
Sattlegger, E.Ein Einblick in die Forschung eines wichtigen Signaltransduktionsweges. [Insights into the research on an important signal transduction pathway] 22 Sept 2011. Presented at University of Applied Sciences, Hamburg, Germany.
[Oral Presentation]Authored by: Sattlegger, E.
Sattlegger, E.The newest findings on Gcn2 regulation. 16 Sept 2011. Presented at Gerhard-August University Goettingen, Germany.
[Oral Presentation]Authored by: Sattlegger, E.
Sattlegger, E., & Munn, A.N/A this is science art: Designed science art image for Journal Cover, together with Alan Munn, Griffith University, Australia, for the Journal Australian Biochemist, 40(2):9-13. (pp. cover - cover).
[Other]Authored by: Sattlegger, E.
Sattlegger, E.Binding of Gcn proteins to ribosomes – what do we know so far?. Presented at Max Planck Institute of Molecular Genetics and Charité joint Seminar, Berlin, Germany.
[Oral Presentation]Authored by: Sattlegger, E.
Sattlegger, E.Cytoskeletal effects on sensing amino acid starvation: when amino acid hunger is actin up. Presented at University of Nebraska, Omaha, NE.
[Oral Presentation]Authored by: Sattlegger, E.

Consultancy and Languages

Languages

  • German
    Last used: - current
    Spoken ability: Excellent
    Written ability: Excellent
  • English
    Last used: - current
    Spoken ability: Excellent
    Written ability: Excellent

Supervision and Teaching

Summary of Doctoral Supervision

Position Current Completed
Supervisor 1 4
CoSupervisor 1 3

Teaching

Undergraduate papers:

122.101/221 - Biochemistry of Cells/Foods

122.233 - Metabolic Biochemistry (paper coordinator)

162.101 - Biology of Cells

203.340 - Applied Molecular Biology

Postgraduate papers:

122.703 - Gene expression (paper coordinator)

122.704 - Molecular Cell Biology (paper coordinator only)

162.760 - Research Methods (paper coordinator)

and other papers as required

Media and Links

Other Links


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