203.300 DNA Technology
DNA Structure
DNA Protein Interactions
INTRODUCTIONWith any luck (and a lot of hard work on your behalf) this will be your last year of undergraduate study. To help you learn all you will need this year, there are another set of tutorials for you to work through. If you have not used these tutorials or the program RasMol in previous years, then I suggest you visit the instructions page before you go on. If you know what you are doing and are confident wit h the format of the previous years tutorials, then carry on. There are a few sections to this years work...
So far you have encountered one particular type of DNA-structure. In this set of tutorials, you will learn about how flexible the DNA chain is, different forms of the molecules which make DNA, and different models of DNA. It would make the most sense to
you if you go through these tutorials in the order they are below.
Fundamental DNA Structure
Standard DNA Model
Variations of Structure
DNA INTERACTIONS
This section involves the interactions which occur between DNA and both Drugs and Proteins. There are specific examples of the interactions between Proteins and DNA that are to be worked through. Also, the interactions between the strands of DNA are rev
ised, with the melting and reannealing processes involved.
DNA & Drug Interactions
DNA & Protein Interactions - Non Specific
DNA & EcoR1
DNA & CAP
DNA & Zinc FInger Proteins
DNA & TATA Binding Protein
DNA Denaturing & Reannealing