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Downstream Bioseparations


Production of recombinant human alpha-1-antitrypsin.
 
 

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Selected Publications

Chisti, Y. and Moo-Young, M., Biotechnol. Adv., 8, 699-708 (1990). Large scale protein separations: Engineering aspects of chromatography.

Chisti, Y. and Moo-Young, M., J. Ind. Microbiol., 13, 201-207 (1994). Clean-in-place systems for industrial bioreactors: Design, validation and operation.

Garrido, F., Banerjee, U. C., Chisti, Y., and Moo-Young, M., Bioseparation, 4, 319-328 (1994). Disruption of a recombinant yeast for the release of beta-galactosidase.

Zhang, Z., Chisti, Y., and Moo-Young, M., Bioseparation, 5, 329-337 (1995). Isolation of a recombinant intracellular beta-galactosidase by ammonium sulfate fractionation of cell homogenates.

Chisti, Y., in Bioseparation and Bioprocessing: A Handbook, vol. 2, Subramanian, G., ed, Wiley-VCH, New York, 1998, pp. 3-30. Strategies in downstream processing.

Chisti, Y. and Moo-Young, M., in Biotechnology: The Science and the Business, second edition, Moses, V., Cape, R. E., and Springham, D. G., editors, Harwood Academic Publishers, New York, 1999, pp. 177-222. Fermentation technology, bioprocessing, scale-up and manufacture.

Belarbi, E. H., Molina, E., and Chisti, Y., Enzyme Microb. Technol., 26, 516–529 (2000). A process for high yield and scaleable recovery of high purity eicosapentaenoic acid esters from microalgae and fish oil.

Tamer, I. M. and Chisti, Y., Enzyme Microb. Technol., 29, 611–620 (2001). Production and recovery of recombinant protease inhibitor alpha-1-antitrypsin.

Sharma, R., Chisti, Y., and Banerjee, U. C., Biotechnol. Adv., 19, 627–662 (2001). Production, purification, characterization, and applications of lipases.