Biopharmaceuticals and Vaccines

Bioprocesses for producing recombinant biopharmaceuticals, vaccines, and other therapeutics.

Selected Publications

Chisti, Y. and Moo-Young, M., in Biotechnology: The Science and the Business, second edition, Moses, V., Cape, R. E., and Springham, D. G., editors, Harwood Academic Publishers, New York, 1999, pp. 177-222. Fermentation technology, bioprocessing, scale-up and manufacture.

Chisti, Y., in Encyclopedia of Food Microbiology, Robinson, R., Batt, C., and Patel, P., editors, Academic Press, London, 1999, pp. 663-674. Fermentation (industrial): Basic considerations.

Rouf, S. A., Moo-Young, M., and Chisti, Y., Biotechnol. Adv., 14, 239-266 (1996). Tissue-type plasminogen activator: Characteristics, applications and production technology.

Tamer, I. M. and Chisti, Y., Enzyme Microb. Technol., 29, 611-620 (2001). Production and recovery of recombinant protease inhibitor alpha-1-antitrypsin.

Zhang, Z., Chisti, Y., and Moo-Young, M., J. Biotechnol., 43, 33-40 (1995). Effects of the hydrodynamic environment and shear protectants on survival of erythrocytes in suspension.

García Camacho, F., Molina Grima, E., Sánchez Mirón, A., González Pascual, V., and Chisti, Y., Enzyme Microb. Technol., 29, 602-610 (2001). Carboxymethyl cellulose protects algal cells against hydrodynamic stress.

Chisti, Y., Crit. Rev. Biotechnol., 21, 67-110 (2001). Hydrodynamic damage to animal cells.

Chisti, Y., Trends Biotechnol., 18, 420-432 (2000). Animal-cell damage in sparged bioreactors.