Asif Zia

Thesis Title
Smart Electrochemical Sensing System for the Real Time Detection of Endocrine Disrupting Compounds and Hormones

Read article at Massey Research Online:

A regular ingestion of synthetic teratogenic compounds that have leached out from plastic food packaging is the major source of genetic, epigenetic and developmental defects leading to cancer, diabetes, obesity and cardiovascular diseases in human beings. Mr Asif developed a smart electrochemical sensing system that could be used as a prognostic tool to quantify concentration level of endocrine toxins that have leached into plastic-packaged drinking water, juices and beverages up to parts per billion. He immobilized the molecular imprinted polymer coating, also known as "artificial antibodies", on the sensing surface of an electromagnetically driven microelectromechanical interdigital transducer to achieve selectivity for the targeted toxin molecules in the fluid medium. Contrary to the current methods available for detection of endocrine toxins and hormones, the developed real-time technique displayed the potential to emerge as a rapid chemical analysing procedure that was non-invasive, low-cost, robust, and did not require hi-tech equipment and professional expertise for real world applications.

Supervisors
Professor Subhas Mukhopadhyay
Associate Professor Pak Yu
Associate Professor Ibrahim Al-Bahadly

Zia, A. I., Mukhopadhyay, S. C., Yu, P.-L., Al-Bahadly, I., Gooneratne, C. P., & Kosel, J. (2014). Rapid and molecular selective electrochemical sensing of phthalates in aqueous solution. Biosensors and Bioelectronics.

Zia, A., Mukhopadhyay, S., Yu, P., Al-Bahadly, I., Gooneratne, C., & Kosel, J. (2014). Post Annealing Performance Evaluation of Printable Interdigital Capacitive Sensors by Principal Component Analysis. Sensors Journal, IEEE, PP(99), 1-1. doi: 10.1109/jsen.2014.2355224

Zia, A. I., Rahman, M. S. A., Mukhopadhyay, S. C., Yu, P.-L., Al-Bahadly, I., Gooneratne, C. P., . . . Liao, T.-S. (2013). Technique for rapid detection of phthalates in water and beverages. Journal of Food Engineering, 116(2), 515-523.

Zia, A. I., Syaifudin, A. M., Mukhopadhyay, S., Yu, P., Al-Bahadly, I., Gooneratne, C. P., . . . Liao, T.-S. (2013). Electrochemical impedance spectroscopy based MEMS sensors for phthalates detection in water and juices. Journal of Physics: Conference Series, 439, 012026.

Zia, A. I., Mohd Syaifudin, A. R., Mukhopadhyay, S. C., Al-Bahadly, I. H., Yu, P. L., Gooneratne, C. P., . . . Liao, T.-S. (2013, 6-9 May 2013). MEMS based impedimetric sensing of phthalates. Paper presented at the Instrumentation and Measurement Technology Conference (I2MTC), 2013 IEEE International.

AI Zia, S. C. M., P.L.Yu, I. H. Al Bahadly. (2013). Ovarian Hormone Estrone Glucuronide (E1G) Quantification- Impedimetric Electrochemical Spectroscopy Approach. Paper presented at the Sensing Technology (ICST), 2013 Seventh International Conference.

ia, A. I., Mohd Syaifudin, A., Mukhopadhyay, S., Yu, P., Al-Bahadly, I., Kosel, J., & Gooneratne, C. (2012). Sensor and instrumentation for progesterone detection. Paper presented at the Instrumentation and Measurement Technology Conference (I2MTC), 2012 IEEE International.

Syaifudin, A., Zia, A. I., Mukhopadhyay, S., Yu, P., Gooneratne, C. P., & Kosel, J. (2012). Improved detection limits of bacterial endotoxins usingnew type of planar interdigital sensors. Paper presented at the Sensors, 2012 IEEE.

Zia, A. I., Mohd Syaifudin, A., Mukhopadhyay, S., Al-Bahadly, I., Yu, P., Gooneratne, C., & Kosel, J. (2011). Development of Electrochemical Impedance Spectroscopy based sensing system for DEHP detection. Paper presented at the Sensing Technology (ICST), 2011 Fifth International Conference.

Zia, A. I., Mukhopadhyay, S., Al-Bahadly, I., Yu, P., Gooneratne, C. P., & Kosel, J. (2014). Introducing molecular selectivity in rapid impedimetric sensing of phthalates. Paper presented at the Instrumentation and Measurement Technology Conference (I2MTC) Proceedings, 2014 IEEE International.

AI Zia, S.C.M., P.L.Yu, I. H. Al Bahadly, (2014). “Development and Evaluation of Portable Low Cost Testing System for Phthalates”, 2014, Proceedings of the 8th International Conference on Sensing Technology (ICST). Sep. 2-4, 2014, Liverpool, UK. pp. 385 - 391