Sarah Taylor

Citation

Thesis Title
Novel models of tendon injury and gap junction modulation in tendon cell and tissue repair

Read article at Massey Research Online:

Tendon injury is a major welfare and financial problem in horses and humans. Miss Taylor’s research involved developing and testing  models of acute tendon injury in both sheep and horses. These were used to study structural and functional changes in tendons and used a number of methods including ultrasound imaging and a number of molecular methods to target gap junctions that link cells and are involved in the spread of cell death following injury. The ability to modulate these gap junctions would therefore provide a potential intervention strategy to assist tendon healing.  Miss Taylor’s results show that sheep and horse systems respond differently to intervention strategies and thus provide very useful experimental systems to further study mechanisms of tendon wound healing that could lead to a therapeutic treatment regimen.

Supervisors
Professor Kathryn Stowell
Ms Chris Thomson