Contact details +64 (09) 414 0800 ext. 43646

Dr Kay Rutherfurd-Markwick

Associate Professor in Pathophysiology

School of Health Sciences

I have considerable experience investigating the effects of dietary supplementation (including probiotics) on immune function in a wide range of species, including humans, cats, dogs, mice and chickens. This research work has assisted in the development of functions foods for humans. Two new dairy products sold by Fonterra into Asia since 2000 were a result of my research work. The probiotic strain, DR10 (HN019 in publications), was originally marketed in Fernleaf DefenseÔ (winner of the Trade NZ Food Export Award, 2000) and has now been licensed to Danisco one of the world’s largest ingredient companies.

I have also worked for a number of years investigating the biochemistry of unusual sulphur amino acids such as felinine and isovalthine which are excreted in cat urine. Recent work has focused on determining the mechanism of felinine formation and the isolation and identification of other felinine containing excretion products such as Acetyl-felinine, and also determining the effects of dietary supplementation on isovalthine excretion. This felinine research work has proved to be ground-breaking, and has made a significant contribution to new knowledge in sulphur amino acid metabolism in cats. Current research is extending this work with a research project aimed to determine if humans with certain metabolic disorders such as severe diabetes, hypercholesterolaemia and hypothyroidism excrete isovalthine.

New areas of research include the expansion of techniques developed in animals for use in humans in a project which aims to correlate electrolyte levels in serum, saliva, sweat and urine in resting and exercising humans

Considerable experience investigating the effects of dietary supplementation (including probiotics) on immune function in a wide range of species (humans, cats, dogs, mice, chickens). Have also worked for a number of years investigating the biochemistry of unusual sulphur amino acids eg. felinine and isovalthine (excreted in cat urine), This felinine research work has proved to be ground-breaking, and has made a significant contribution to new knowledge in sulphur amino acid metabolism in cats. Current research is extending this work with a project aimed to determine if humans with certain metabolic disorders such as severe diabetes, hypercholesterolaemia and hypothyroidism excrete isovalthine.

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Professional

Contact details

Ph: 094140800 EXT:43646
Location: Level 3, Sir Neil Waters Extension
Campus: Albany

Research Expertise

Research Interests

Immunology, Bioactive Peptides/Proteins, Functional Foods, Probiotics, Protein Chemistry, Nutritional Biochemistry for Companion Animals

Thematics

Health and Well-being

Area of Expertise

Field of research codes
Analytical Biochemistry (060101): Biochemistry and Cell Biology (060100): Biological Sciences (060000): Cell Development, Proliferation and Death (060103): Cell Metabolism (060104):
Clinical Chemistry (diagnostics) (110302): Clinical Sciences (110300):
Enzymes (060107):
Medical And Health Sciences (110000): Medical Biochemistry and Metabolomics (110100): Medical Biochemistry: Amino Acids and Metabolites (110101): Medical Biochemistry: Proteins and Peptides (incl. Medical Proteomics) (110106): Nutrition and Dietetics (111100): Pathology (110316)

Keywords

Immunology, Bioactive Peptides/Proteins, Functional Foods, Probiotics, Protein Chemistry, Nutritional Biochemistry for Companion Animals, Method Development

Research Projects

Summary of Research Projects

Position	Current	Completed
Project Leader	2	7
Team Member	0	2

Research Outputs

Journal

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Stanaway, L., Rutherfurd-Markwick, K., Page, R., Wong, M., Jirangrat, W., Teh, KH., . . . Ali, A. (2019). Acute supplementation with nitrate-rich beetroot juice causes a greater increase in plasma nitrite and reduction in blood pressure of older compared to younger adults. Nutrients. 11(7)
[Journal article]Authored by: Ali, A., Page, R., Rutherfurd, K.

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Rapisura-Flores, JA., Morel, PCH., Thomas, DG., Wilkinson, BHP., Rutherfurd-Markwick, K., & Purchas, RW. (2019). Intestinal histology and immune status of semi-anemic piglets fed lactoferrin, meat, or meat extract. Philippine Journal of Science. 148(1), 113-118
[Journal article]Authored by: Morel, P., Rutherfurd, K., Thomas, D.

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Juggett, J., Nowak, E., Rutherfurd-Markwick, K., & Mutukumira, A. (2018). Encapsulation of Curcumin by milk and whey powders using spray drying. Advances in Food Processing and Technology. 2018(2),
[Journal article]Authored by: Mutukumira, A., Nowak, E., Rutherfurd, K.

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Southward, K., Rutherfurd-Markwick, K., Badenhorst, C., & Ali, A. (2018). Response to “are there non-responders to the ergogenic 3 effects of caffeine ingestion on exercise performance?”. Nutrients. 10(11)
[Journal article]Authored by: Ali, A., Badenhorst, C., Rutherfurd, K.

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Southward, K., Rutherfurd-Markwick, K., Badenhorst, C., & Ali, A. (2018). The role of genetics in moderating the inter-individual differences in the ergogenicity of caffeine. Nutrients. 10(10)
[Journal article]Authored by: Ali, A., Badenhorst, C., Rutherfurd, K.

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Ali, A., Starck, C., Wham, C., Wolber, F., Dickens, M., Thunders, M., . . . Rutherfurd, K. (2018). The highs and lows of caffeine intake in New Zealand children. Journal of Caffeine Research. 8(3) Retrieved from https://www.liebertpub.com/doi/10.1089/caff.2017.0035
[Journal article]Authored by: Ali, A., Dickens, M., O'Keeffe, K., Rutherfurd, K., Thomas, J., Wham, C., Wolber, F.

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Southward, K., Rutherfurd-Markwick, KJ., & Ali, A. (2018). Correction to: The Effect of Acute Caffeine Ingestion on Endurance Performance: A Systematic Review and Meta–Analysis (Sports Medicine, (2018), 48, 8, (1913-1928), 10.1007/s40279-018-0939-8). Sports Medicine. 48(10), 2425-2441
[Journal article]Authored by: Ali, A., Rutherfurd, K.

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Southward, K., Rutherfurd-Markwick, KJ., & Ali, A. (2018). The Effect of Acute Caffeine Ingestion on Endurance Performance: A Systematic Review and Meta–Analysis. Sports Medicine. 48(8), 1913-1928
[Journal article]Authored by: Ali, A., Rutherfurd, K.

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Lee, V., Rutherfurd-Markwick, K., & Ali, A. (2018). Effect of carbohydrate ingestion during cycling exercise on affective valence and activation in recreational exercisers. Journal of Sports Sciences. 36(3), 340-347
[Journal article]Authored by: Ali, A., Rutherfurd, K.

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Wham, C., Rowe, K., Ali, A., & Rutherfurd-Markwick, KJ. (2017). Influences of caffeine consumption among adult New Zealanders: a qualitative study. Journal of Caffeine Research. 7(4), 142-150 Retrieved from https://www.liebertpub.com/doi/pdf/10.1089/jcr.2017.0020
[Journal article]Authored by: Ali, A., Rutherfurd, K., Wham, C.

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Stanaway, L., Rutherfurd-Markwick, K., Page, R., & Ali, A. (2017). Performance and health benefits of dietary nitrate supplementation in older adults: A systematic review. Nutrients. 9(11)
[Journal article]Authored by: Ali, A., Page, R., Rutherfurd, K.

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Rutherfurd-Markwick, K., Starck, C., Dulson, DK., & Ali, A. (2017). Salivary diagnostic markers in males and females during rest and exercise. Journal of the International Society of Sports Nutrition. 14(1)
[Journal article]Authored by: Ali, A., Rutherfurd, K.

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Rutherfurd-Markwick, KJ., & Ali, A. (2016). Caffeine use in the 21st Century: Considerations for public health. Jacobs Journal of Food and Nutrition. 3(1), 1-10
[Journal article]Authored by: Ali, A., Rutherfurd, K.

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Ali, A., O'Donnell, J., Foskett, A., & Rutherfurd-Markwick, K. (2016). The influence of caffeine ingestion on strength and power performance in female team-sport players. Journal of the International Society of Sports Nutrition. 13(1)
[Journal article]Authored by: Ali, A., Foskett, A., Rutherfurd, K.

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Ali, A., O Donnell, J., Von Hurst, P., Foskett, A., Holland, S., Starck, C., . . . Rutherfurd-Markwick, K. (2016). Caffeine ingestion enhances perceptual responses during intermittent exercise in female team-game players. Journal of Sports Sciences. 34(4), 330-341
[Journal article]Authored by: Ali, A., Foskett, A., Rutherfurd, K., Von Hurst, P.

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Hill, S., Rutherfurd-Markwick, K., Ravindran, G., & Thomas, DG. (2015). The effects of the proportions of dietary macronutrients on the digestibility and post-prandial endocrine responses in domestic cats (Felis catus) 2015. Journal of Applied Animal Nutrition. 3, 1-9
[Journal article]Authored by: Rutherfurd, K., Thomas, D.

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O'Brien, T., Thomas, DG., Morel, PCH., & Rutherfurd-Markwick, KJ. (2015). Moderate dietary supplementation with vitamin E enhances lymphocyte functionality in the adult cat. Research in Veterinary Science. 99, 63-69
[Journal article]Authored by: Morel, P., Rutherfurd, K., Thomas, D.

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Ali, A., O'Donnell, JM., Starck, C., & Rutherfurd-Markwick, KJ. (2015). The effect of caffeine ingestion during evening exercise on subsequent sleep quality in females. International Journal of Sports Medicine. 36(6), 433-439
[Journal article]Authored by: Ali, A., Rutherfurd, K.

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O'Brien, T., Thomas, DG., Morel, PCH., & Rutherfurd-Markwick, KJ. (2014). Moderate dietary supplementation with vitamin E enhances lymphocyte functionality in the adult cat. Research in Veterinary Science.
[Journal article]Authored by: Morel, P., Rutherfurd, K.

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Moughan, PJ., & Rutherfurd-Markwick, K. (2013). Food bioactive proteins and peptides: Antimicrobial, immunomodulatory and anti-inflammatory effects. , 313-340
[Journal article]Authored by: Moughan, P., Rutherfurd, K.

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Rutherfurd-Markwick, KJ., Hendriks, WH., Morel, PCH., & Thomas, DG. (2013). The potential for enhancement of immunity in cats by dietary supplementation. Veterinary Immunology and Immunopathology. 152(3-4), 333-340
[Journal article]Authored by: Morel, P., Rutherfurd, K., Thomas, D.

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Rutherfurd-Markwick, KJ. (2012). Food proteins as a source of bioactive peptides with diverse functions. British Journal of Nutrition. 108(SUPPL. 2)
[Journal article]Authored by: Rutherfurd, K.

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Singh, I., Tucker, LA., Gendall, P., Rutherfurd-Markwick, KJ., Cline, J., & Thomas, DG. (2011). Age, breed, sex distribution and nutrition of a population of working farm dogs in New Zealand: Results of a crosssectional study of members of the New Zealand sheep dog trial association. New Zealand Veterinary Journal. 59(3), 133-138
[Journal article]Authored by: Rutherfurd, K., Thomas, D.

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Balan, P., Han, KS., Rutherfurd-Markwick, K., Singh, H., & Moughan, PJ. (2011). Ovine serum immunoglobulin has immunomodulatory effects in growing rats gavaged with Salmonella enteritidis. Journal of Nutrition. 141(5), 950-956
[Journal article]Authored by: Balan, P., Moughan, P., Rutherfurd, K., Singh, H.

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Balan, P., Han, KS., Rutherfurd-Markwick, K., Singh, H., & Moughan, PJ. (2010). Immunomodulatory effects of ovine serum immunoglobulin in the growing rat. Animal. 4(10), 1702-1708
[Journal article]Authored by: Balan, P., Moughan, P., Rutherfurd, K., Singh, H.

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Hill, SR., Rutherfurd-Markwick, KJ., Ravindran, G., Thomas, DG., & Ugarte, CE. (2009). The effects of the proportions of dietary macronutrients on the digestibility, post-prandial endocrine responses and large intestinal fermentation of carbohydrate in working dogs. New Zealand Veterinary Journal. 57(6), 313-318
[Journal article]Authored by: Rutherfurd, K., Thomas, D.

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Hendriks, WH., Rutherfurd-Markwick, KJ., Weidgraaf, K., Morton, RH., & Rogers, QR. (2008). Urinary felinine excretion in intact male cats is increased by dietary cystine. British Journal of Nutrition. 100(4), 801-809
[Journal article]Authored by: Rutherfurd, K., Weidgraaf, K.

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Hendriks, WH., Rutherfurd-Markwick, KJ., Weidgraaf, K., Ugarte, C., & Rogers, QR. (2008). Testosterone increases urinary free felinine, N-acetylfelinine and methylbutanolglutathione excretion in cats (Felis catus). Journal of Animal Physiology and Animal Nutrition. 92(1), 53-62
[Journal article]Authored by: Rutherfurd, K., Weidgraaf, K.

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Torbatinejad, NM., Annison, G., Rutherfurd-Markwick, K., & Sabine, JR. (2007). Structural constituents of the seagrass Posidonia australis. Journal of Agricultural and Food Chemistry. 55(10), 4021-4026
[Journal article]Authored by: Rutherfurd, K.

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Rutherfurd, SM., Rutherfurd-Markwick, KJ., & Moughan, PJ. (2007). Available (ileal digestible reactive) lysine in selected pet foods. Journal of Agricultural and Food Chemistry. 55(9), 3517-3522
[Journal article]Authored by: Moughan, P., Rutherfurd, K.

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Rutherfurd-Markwick, KJ., McGrath, MC., Weidgraaf, K., & Hendriks, WH. (2006). γ-Glutamylfelinylglycine metabolite excretion in the urine of the domestic cat (Felis catus). Journal of Nutrition. 136(7)
[Journal article]Authored by: Rutherfurd, K., Weidgraaf, K.

Crooks, CV., Wall, CR., Cross, ML., & Rutherfurd-Markwick, KJ. (2006). The effect of bovine colostrum supplementation on salivary IgA in distance runners. International Journal of Sport Nutrition and Exercise Metabolism. 16(1), 47-64
[Journal article]Authored by: Rutherfurd, K.

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Rutherfurd-Markwick, KJ., Johnson, D., Cross, ML., & Gill, HS. (2005). Modified milk powder supplemented with immunostimulating whey protein concentrate (IMUCARE) enhances immune function in mice. Nutrition Research. 25(2), 197-208
[Journal article]Authored by: Rutherfurd, K.

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Rutherfurd-Markwick, KJ., & Gill, HS. (2005). Immunomodulating activity of protein concentrates derived from bovine milk whey in mice. Nutrition Research. 25(2), 157-166
[Journal article]Authored by: Rutherfurd, K.

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Rutherfurd, KJ., Rogers, QR., & Hendriks, W. (2005). Mammalian isovalthine metabolism. Journal of Animal Physiology and Animal Nutrition. 89(1-2), 1-10
[Journal article]Authored by: Rutherfurd, K.

Rutherfurd-Markwick, KJ., & Moughan, PJ. (2005). Bioactive peptides derived from food. Journal of AOAC International. 88(3), 955-966
[Journal article]Authored by: Moughan, P., Rutherfurd, K.

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Rutherfurd Markwick, KJ., Johnson, D., Cross, ML., & Gill, HS. (2005). Modified milk powder supplemented with immunostimulating whey protein concentrate (IMUCARE) enhances immune function in mice. Nutrition Research. 25, 192-203
[Journal article]Authored by: Rutherfurd, K.

Rutherfurd-Markwick, KJ., Rogers, QR., & Hendriks, WH. (2005). Mammalian isovalthine metabolism. Journal of Animal Physiology and Animal Nutrition. 89(1-2), 1-10
[Journal article]Authored by: Rutherfurd, K.

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Zhou, JS., Rutherfurd, KJ., & Gill, HS. (2005). Inability of probiotic bacterial strains Lactobacillus rhamnosus HN001 and Bifidobacterium lactis HN019 to induce human platelet aggregation in vitro. Journal of Food Protection. 68(11), 2459-2464
[Journal article]Authored by: Rutherfurd, K.

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Hendriks, WH., Vather, R., Rutherfurd, SM., Weidgraaf, K., & Rutherfurd-Markwick, KJ. (2004). Urinary isovalthine excretion in adult cats is not gender dependent or increased by oral leucine supplementation. Journal of Nutrition. 134(8 SUPPL.)
[Journal article]Authored by: Rutherfurd, K., Weidgraaf, K.

Hendriks, WH., Harding, DRK., & Rutherfurd-Markwick, KJ. (2004). Isolation and characterisation of renal metabolites of γ- glutamylfelinylglycine in the urine of the domestic cat (Felis catus). Comparative Biochemistry and Physiology - B Biochemistry and Molecular Biology. 139(2), 245-251
[Journal article]Authored by: Harding, D., Rutherfurd, K.

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Low, PPL., Rutherfurd, KJ., Gill, HS., & Cross, ML. (2003). Effect of dietary whey protein concentrate on primary and secondary antibody responses in immunized BALB/c mice. International Immunopharmacology. 3(3), 393-401
[Journal article]Authored by: Rutherfurd, K.

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Hendriks, WH., Wu, YB., Shields, RG., Newcomb, M., Rutherfurd, KJ., Belay, T., . . . Wilson, J. (2002). Vitamin E requirement of adult cats increases slightly with high dietary intake of polyunsaturated fatty acids. Journal of Nutrition. 132(6 SUPPL. 1)
[Journal article]Authored by: Rutherfurd, K.

Hayman, A., MacGibbon, A., Pack, RJ., Rutherfurd, K., & Green, JH. (2002). High intake, but not low intake, of CLA impairs weight gain in growing mice. Lipids. 37(7), 689-692
[Journal article]Authored by: Rutherfurd, K.

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Rutherfurd, KJ., Rutherfurd, SM., Moughan, PJ., & Hendriks, WH. (2002). Isolation and characterization of a Felinine-containing peptide from the blood of the domestic cat (Felis catus). Journal of Biological Chemistry. 277(1), 114-119
[Journal article]Authored by: Moughan, P., Rutherfurd, K.

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Gill, HS., Rutherfurd, KJ., Cross, ML., & Gopal, PK. (2001). Enhancement of immunity in the elderly by dietary supplementation with the probiotic Bifidobactedum lactis HN019. American Journal of Clinical Nutrition. 74(6), 833-839
[Journal article]Authored by: Rutherfurd, K.

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Gill, HS., Cross, ML., Rutherfurd, KJ., & Gopal, PK. (2001). Dietary probiotic supplementation to enhance cellular immunity in the elderly. British Journal of Biomedical Science. 58(2), 94-96
[Journal article]Authored by: Rutherfurd, K.

Hendricks, WH., Rutherfurd, SM., & Rutherfurd, KJ. (2001). Importance of sulfate, cysteine and methionine as precursors to felinine synthesis by domestic cats (Felis catus). Comparative Biochemistry and Physiology Part C. 129(3), 211-216
[Journal article]Authored by: Rutherfurd, K.

Gill, HS., Shu, Q., Lin, H., Rutherfurd, KJ., & Cross, ML. (2001). Protection against translocating Salmonella typltimurium infection in mice by feeding the immuno-enhancing probiotic Lactobacillus rhamnosus strain HN001. Medical Microbiology and Immunology. 190(3), 97-104
[Journal article]Authored by: Rutherfurd, K.

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Low, PPL., Rutherfurd, KJ., Cross, ML., & Gill, HS. (2001). Enhancement of mucosal antibody responses by dietary whey protein concentrate. Food and Agricultural Immunology. 13(4), 255-264
[Journal article]Authored by: Rutherfurd, K.

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Gill, HS., & Rutherfurd, KJ. (2001). Viability and dose-response studies on the effects of the immunoenhancing lactic acid bacterium Lactobacillus rhamnosus in mice. British Journal of Nutrition. 86(2), 285-289
[Journal article]Authored by: Rutherfurd, K.

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Gill, HS., Rutherfurd, KJ., & Cross, ML. (2001). Dietary probiotic supplementation enhances natural killer cell activity in the elderly: An investigation of age-related immunological changes. Journal of Clinical Immunology. 21(4), 264-271
[Journal article]Authored by: Rutherfurd, K.

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Gill, HS., & Rutherfurd, KJ. (2001). Immune enhancement conferred by oral delivery of Lactobacillus rhamnosus HN001 in different milk-based substrates. Journal of Dairy Research. 68(4), 611-616
[Journal article]Authored by: Rutherfurd, K.

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Gill, HS., & Rutherfurd, KJ. (2001). Probiotic supplementation to enhance natural immunity in the elderly: Effects of a newly characterized immunostimulatory strain Lactobacillus rhamnosus HN001 (DR20™) on leucocyte phagocytosis. Nutrition Research. 21(1-2), 183-189
[Journal article]Authored by: Rutherfurd, K.

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Hendriks, WH., Rutherfurd, SM., & Rutherfurd, KJ. (2001). Importance of sulfate, cysteine and methionine as precursors to felinine synthesis by domestic cats (Felis catus). Comparative Biochemistry and Physiology - C Toxicology and Pharmacology. 129(3), 211-216
[Journal article]Authored by: Rutherfurd, K.

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Gill, HS., Rutherfurd, KJ., Prasad, J., & Gopal, PK. (2000). Enhancement of natural and acquired immunity by Lactobacillus rhamnosus (HN001), Lactobacillus acidophilus (HN017) and Bifidobacterium lactis (HN019). British Journal of Nutrition. 83(2), 167-176
[Journal article]Authored by: Rutherfurd, K.

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Gill, HS., Doull, F., Rutherfurd, KJ., & Cross, ML. (2000). Immunoregulatory peptides in bovine milk. British Journal of Nutrition. 84(SUPPL. 1)
[Journal article]Authored by: Rutherfurd, K.

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Rutherfurd, KJ., & Gill, HS. (2000). Peptides affecting coagulation. British Journal of Nutrition. 84(SUPPL. 1)
[Journal article]Authored by: Rutherfurd, K.

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Shu, Q., Lin, H., Rutherfurd, KJ., Fenwick, SG., Prasad, J., Gopal, PK., . . . Gill, HS. (2000). Dietary Bifidobacterium lactis (HN019) enhances resistance to oral Salmonella typhimurium infection in mice. Microbiology and Immunology. 44(3), 213-222
[Journal article]Authored by: Rutherfurd, K.

Zhou, JS., Shu, Q., Rutherfurd, KJ., Prasad, J., Gopal, PK., & Gill, HS. (2000). Acute oral toxicity and bacterial translocation studies on potentially probiotic strains of lactic acid bacteria. Food and Chemical Toxicology. 38(2-3), 153-161
[Journal article]Authored by: Rutherfurd, K.

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Shu, Q., Lin, H., Rutherfurd, KJ., Gill, HS., Rutherfurd, KJ., Prasad, J., . . . Fenwick, SG. (2000). Dietary bifidobacterium lactis (hn019) enhances resistance to oral salmonella typhimurium infection in mice. Microbiology and Immunology. 44(3), 213-222
[Journal article]Authored by: Rutherfurd, K.

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Zhou, JS., Shu, Q., Rutherfurd, KJ., Prasad, J., Birtles, MJ., Gopal, PK., . . . Gill, HS. (2000). Safety assessment of potential probiotic lactic acid bacterial strains Lactobacillus rhamnosus HN001, Lb. acidophilus HN017, and Bifidobacterium lactis HN019 in BALB/c mice. International Journal of Food Microbiology. 56(1), 87-96
[Journal article]Authored by: Rutherfurd, K.

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Shu, Q., Zhou, JS., J Rutherfurd, K., Birtles, MJ., Prasad, J., Gopal, PK., . . . Gill, HS. (1999). Probiotic lactic acid bacteria (Lactobacillus acidophilus HN017, Lactobacillus rhamnosus HN001 and Bifidobacterium lactis HN019) have no adverse effects on the health of mice. International Dairy Journal. 9(11), 831-836
[Journal article]Authored by: Rutherfurd, K.

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Rutherfurd, KJ., Chou, JY., & Mansfield, BC. (1995). A motif in PSG11s mediates binding to a receptor on the surface of the promonocyte cell line THP-1. Molecular Endocrinology. 9(10), 1297-1305
[Journal article]Authored by: Rutherfurd, K.

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McLenachan, PA., Rutherfurd, KJ., Beggs, KT., Sims, SE., & Mansfield, BC. (1994). Characterization of the PSG11 gene. Genomics. 22(2), 356-363
[Journal article]Authored by: McLenachan, P., Rutherfurd, K.

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Rutherfurd, KJ., Swiderek, KM., Green, CB., Chen, S., Shively, JE., & Kwok, SCM. (1992). Purification and characterization of PSP-I and PSP-II, two major proteins from porcine seminal plasma. Archives of Biochemistry and Biophysics. 295(2), 352-359
[Journal article]Authored by: Rutherfurd, K.

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Rutherfurd, KJ., Chen, S., & Shively, JE. (1991). Affinity Labeling of Bovine Adrenal 3β-Hydroxysteroid Dehydrogenase/Steroid Isomerase by 5′-[p-(Fluorosulfonyl)benzoyl]adenosine. Biochemistry. 30(33), 8116-8123
[Journal article]Authored by: Rutherfurd, K.

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Rutherfurd, KJ., Chen, S., & Shively, JE. (1991). Isolation and Amino Acid Sequence Analysis of Bovine Adrenal 3β-Hydroxysteroid Dehydrogenase/Steroid Isomerase. Biochemistry. 30(33), 8108-8116
[Journal article]Authored by: Rutherfurd, K.

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Book

Moughan, PJ., & Rutherfurd, KJ. (2013). Food bioactive proteins and peptides: Antimicrobial, immunomodulatory and anti-inflammatory effects. In PC. Calder, & P. Yaqoob (Eds.) Diet, Immunity and Inflammation. (pp. 313 - 340). UK: Woodhead Publishing Limited
[Chapter]Authored by: Moughan, P., Rutherfurd, K.

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Moughan, PJ., & Rutherfurd-Markwick, KJ. (2011). Food derived bioactive peptides. In PC. Calder, & P. Yaqoob (Eds.) Diet,Immunity and Inflammation. Cambridge, Great Britain: Woodhead Publishers Ltd
[Chapter]Authored by: Rutherfurd, K.

Rutherfurd Markwick, KJ., & Gill, HS. (2004). Probiotics and immunomodulation. In DA. Hughes, LG. Darlington, & AB. eds (Eds.) Diet and human immune function. (pp. 327 - 344). Totowa, NJ: Humana Press
[Chapter]Authored by: Rutherfurd, K.

Report

Wolber, FM., & Rutherfurd, KJ. (2011). Probiotics for maternal health: immune function and DR20 in pregnancy..
[Commissioned Report]Authored by: Rutherfurd, K., Wolber, F.

Conference

Holland, S., Dickens, M., Wolber, ., heyes, ., & Rutherfurd, . (2017). Soluble factors released by MDA-MB-231 breast cancer cells delay neutrophil apoptosis in vitro.. Poster session presented at the meeting of New Zealand Society for Oncology Conference
[Conference Poster]Authored by: Dickens, M., Heyes, J., Rutherfurd, K., Wolber, F.

Holland, S., Dickens, M., Wolber, F., Heyes, J., & Rutherfurd, KJ. (2017). Soluble factors released by MDA-MB-231 breast cancer cells delay neutrophil apoptosis in vitro.. Poster session presented at the meeting of NZ Med-Sci Congress. Queenstown, New Zealand
[Conference Poster]Authored by: Dickens, M., Heyes, J., Rutherfurd, K., Wolber, F.Contributed to by: Rutherfurd, K.

Grubb, S., Rutherfurd, K., & Mutukumira, A. (2017). Effect of Chordaria cladosiphon (Mozuku) powder on key quality parameters in wheat and gluten-free baked bread. , New Zealand Institute of Food Science and Technology
[Conference Abstract]Authored by: Mutukumira, A., Rutherfurd, K.Contributed to by: Rutherfurd, K.

Thomas, DG., Birmingham, EN., & Rutherfurd-Markwick, KJ. (2016). Defining essential or optimal nutrition in cats and dogs. Nestle Purina Companion Animal Nutrition (CAN) Summit - Pet Nutrition: Beyond Essential. (pp. 1 - 8). : Nestle Purina Companion Animal Nutrition (CAN) Summit - Pet Nutrition: Beyond Essential
[Conference Paper in Published Proceedings]Authored by: Rutherfurd, K., Thomas, D.

Rutherfurd, KJ., & Thomas, DG. (2016). Effects of nutrient supplementation on immune function in cats and dogs. Companion Animal Nutriton Summit Pet Nutrition: Beyond Essential. (pp. 67 - 76). : Nestle Purina Companion Animal Nutrition (CAN) Summit
[Conference Paper in Published Proceedings]Authored by: Rutherfurd, K., Thomas, D.

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Rutherfurd-Markwick, KJ., Hendriks, WH., Morel, PCH., & Thomas, DG. (2013). The potential for enhancement of immunity in cats by dietary supplementation. In Veterinary Immunology and Immunopathology
[Conference Abstract]Authored by: Morel, P., Rutherfurd, K., Thomas, D.

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Carr, AJ., & Rutherfurd-Markwick, KJ. (2012, November). Nutraceutical biopeptides derived from milk. Presented at Inaugural Worldwide Symposium on Milk and Human Health. Seoul, Korea.
[Conference Oral Presentation]Authored by: Rutherfurd, K.

Rutherfurd-Markwick, KJ. (2012). Food proteins as a source of bioactive peptides with diverse functions. In BRITISH JOURNAL OF NUTRITION Vol. 108 (pp. S149 - S157). : CAMBRIDGE UNIV PRESS
[Conference Abstract]Authored by: Rutherfurd, K.Edited by: Henare, S., Moughan, P.

Rutherfurd, KJ., Hendriks, W., McGrath, M., Weidgraaf, K., & Thomas, D. (2010). The potential for enhancement of immunity in cats by dietary supplementation. In The Waltham International Nutritional Sciences Symposium Pet Nutrition - Art or Science?(pp. 49 - 49). , The Waltham International Nutritional Sciences Symposium Pet Nutrition - Art or Science? UK: Waltham International
[Conference Abstract]Authored by: Rutherfurd, K., Thomas, D., Weidgraaf, K.

O'Brien, T., Thomas, D., Morel, P., & Rutherfurd, KJ. (2010). Effect of dietary supplementation with vitamin E and/or selenium on the feline immune system. , The Waltham International Nutritional Sciences Symposium Pet Nutrition - Art or Science?
[Conference Abstract]Authored by: Morel, P., Rutherfurd, K., Thomas, D.

Thomas, DG., Rutherfurd, KJ., Waldron, LA., & Weidgraaf, K. (2010). Influence of a canola-based omega oils source on immunity in mature horses. In The Proceedings of the Australasian Equine Science Symposium 2010 Vol. 3 (pp. 23 - 23). , Australasian Equine Science Symposium 2010 Australia: Australasian Equine Science
[Conference Abstract]Authored by: Rutherfurd, K., Thomas, D., Weidgraaf, K.

Thomas, DG., Rutherfurd, KJ., Waldron, LA., & Weidgraaf, K. (2010). Influence of a commercial omega oils source on digestibility and body condition in mature horses. In Proceedings of the Australasian Equine Science Symposium 2010 Vol. 3 (pp. 24 - 24). , Australasian Equine Science Symposium 2010 Australia: Australasian Equine Science
[Conference Abstract]Authored by: Rutherfurd, K., Thomas, D., Weidgraaf, K.

Rutherfurd, KJ., Thomas, DG., McGrath, M., O'Flaherty, K., & Weidgraaf, K. (2009). Immune enhancing potential of a canola oil-based supplement for the working dog. In Proceedings of the British Society of Animal Science(pp. 066 - 066). , British Society of Animal Science 2009 UK: British Society of Animal Science
[Conference Abstract]Authored by: Rutherfurd, K., Thomas, D., Weidgraaf, K.

Rutherfurd, KJ., McGrath, MC., Weidgraaf, K., Thomas, DG., & Hendriks, WH. (2008). Immune enhancing potential of a canola oil-based supplement in the cat. In "To eat or not to eat?" The Annual Conference The Nutrition Society of New Zealand 2008(pp. 22 - 22). , Annual Conference The Nutrition Society of New Zealand 2008 New Zealand: The Nutrition Society of New Zealand
[Conference Abstract]Authored by: Rutherfurd, K., Thomas, D., Weidgraaf, K.

Palevich, D., Rutherfurd, KJ., Thomas, D., Morel, PCH., & McGrath, M. (2008). Effect of ω-3 and ω-6 fatty acids on cytokine levels in feline whole blood cell cultures. , "To eat or not to eat?" Annual Conference The Nutrition Society of NZ
[Conference Abstract]Authored by: Morel, P., Rutherfurd, K., Thomas, D.

Palevich, D., Rutherfurd, K., Thomas, DG., Morel, PCH., & McGrath, MC. (2008). Effect of ω-3 and ω-6 fatty acids on cytokine levels in feline whole blood cell cultures. In Proceedings of Nutrition Society of New Zealand Vol. 33 (pp. 165 - 165). , Nutrition Society of New Zealand Conference Palmerston North, New Zealand: Nutrition Society of New Zealand
[Conference Abstract]Authored by: Morel, P., Rutherfurd, K., Thomas, D.Edited by: Brough, L.

Weidgraaf, K., Rutherfurd, SM., O'Flaherty, K., Thomas, DG., & Rutherfurd, KJ. (2008). Effect of dietary form on nutrient digestibility in cats and dogs. In Nestle Purina Nutrition Forum: Focus on Felines(pp. 83). : Veterinary Learning Systems: Suppl. to Compendium: Continuing Education for Veterinarians, 30,3(A)
[Conference Abstract]Authored by: Rutherfurd, K., Thomas, D., Weidgraaf, K.

Thomas, DG., Ugarte, CE., Rutherfurd, KJ., & Hendriks, WH. (2008). Effect of a low-protein diet on gut morphology in cats. In Nestle Purina Nutrition Forum: Focus on Felines(pp. 61). : Veterinary Learning Systems: Suppl. to Compendium: Continuing Education for Veterinarians, 30,3(A)
[Conference Abstract]Authored by: Rutherfurd, K., Thomas, D.

Rutherfurd, KJ., McGrath, MC., Morton, RH., Morel, PCH., & Hendriks, WH. (2007). Age-related changes in immune function in cats. , Nestle Purina Nutritional Forum Focus on Felines 2007
[Conference Abstract]Authored by: Morel, P., Rutherfurd, K.

Rutherfurd, KJ., Hendriks, WH., McGrath, MC., Weidgraaf, K., & Thomas, DG. (2007). The potential for enhancement of immunity in cats by feeding yeast-derived nucleotides. In Nutritional Biotechnology in the Feed and Food Industries Vol. Suppl. 1 (pp. 93 - 93). , Alltech's 23rd Annual Symposium Kentucky, USA: Alltech
[Conference Abstract]Authored by: Rutherfurd, K., Thomas, D., Weidgraaf, K.

Singh, J., McCarthy, OJ., Singh, H., Wharemate, ZR., & Rutherfurd, KJ. (2007, June). Physico-chemical and nutritional characteristics of New Zealand Taewa (Maori potato) cultivars. Presented at Food - The Challenges: New Zealand Institute of Food Science and Technology (NZIFST) Conference. Wellington, NZ.
[Conference Oral Presentation]Authored by: Rutherfurd, K., Singh, J.

Rutherfurd-Markwick, KJ., McGrath, MC., Weidgraaf, K., & Hendriks, WH. (2006). gamma-glutamylfelinylglycine metabolite excretion in the urine of the domestic cat (Felis catus). JOURNAL OF NUTRITION. Vol. 136 (pp. 2075S - 2077S). : Symposium on Innovations in Companion Animal Nutrition
[Conference Paper in Published Proceedings]Authored by: Rutherfurd, K., Weidgraaf, K.

Hendriks, W., Rutherfurd Markwick, KJ., Ugarte, CE., & Rogers, QR. (2005). Felinine excretion is modulated by testosterone. (pp. 33). , WALTHAM International Nutritional Sciences Symposium Washington, DC: WALTHAM
[Conference Abstract]Authored by: Rutherfurd, K.

Rutherfurd Markwick, KJ. (2005). The use of pre- and probiotics in the diets of cats and dogs to modulate fermentation. : Wageningen Business School
[Conference Abstract]Authored by: Rutherfurd, K.

Hendriks, W., Vather, R., Rutherfurd, SM., Weidgraaf, K., & Rutherfurd Markwick, KJ. (2004). Urinary isovalthine excretion in adult cats is not gender dependant or increased by oral leucine supplementation. Journal of Nutrition. Vol. 134 (pp. 2114s - 2116s). Bethesda, MD: Waltham International Science Symposium: Nature, Nurture and the Case for Nutrition
[Conference Paper in Published Proceedings]Authored by: Rutherfurd, K., Weidgraaf, K.

Rutherfurd Markwick, KJ., & Hendriks, W. (2003). Functional foods and nutraceuticals for cats and dogs. In TP. Lyons, & KAJ. Eds (Eds.) Alltech's 19th Feed Industry Symposium. (pp. 509 - 519). Nottingham, UK
[Conference Paper in Published Proceedings]Authored by: Rutherfurd, K.

Rutherfurd Markwick, KJ., Rutherfurd, SM., Gill, HS., & Moughan, PJ. (2003). Bioactive peptides and human health. , Worldnutra's 4th International Conference and Exhibition on Nutraceuticals and functional foods
[Conference Abstract]Authored by: Moughan, P., Rutherfurd, K.

Hendriks, WH., Vather, R., Rutherfurd, SM., Weidgraaf, K., & Rutherfurd-Markwick, KJ. (2004). Urinary isovalthine excretion in adult cats is not gender dependent or increased by oral leucine supplementation. JOURNAL OF NUTRITION. Vol. 134 (pp. 2114S - 2116S). : WALTHAM International Science Symposium on Nature, Nurture, and Case for Nutrition
[Conference Paper in Published Proceedings]Authored by: Rutherfurd, K., Weidgraaf, K.

Rutherfurd, SM., Rutherfurd Markwick, KJ., & Hendriks, W. (2002). Model animals for human nutritional studies. Proceedings of the Nutrition Society of New Zealand. Vol. 27 (pp. 25 - 35). Dunedin, NZ: Nutrition Society of New Zealand
[Conference Paper in Published Proceedings]Authored by: Rutherfurd, K.

Zou, M., Rutherfurd, SM., Rutherfurd, KJ., & Moughan, PJ. (2002). Assessment of the accuracy of Atwater's general factors calculating metabolisable energy in New Zealand foodstuffs. Proceedings of the Nutrition Society of New Zealand. Vol. 27 (pp. 117). : 37th Annual Conference of The Nutrition Society of New Zealand
[Conference Paper in Published Proceedings]Authored by: Moughan, P., Rutherfurd, K., Zou, L.

Hendriks, W., Wu, YB., Shields, RG., Newcombe, M., Rutherfurd, KJ., Belay, T., . . . Wilson, J. (2002). Vitamin E requirement of adult cats increases slightly with high dietary intake of polyunsaturated fatty acids. Journal of Nutrition. Vol. 132 (pp. 1613S - 1615S). : Waltham International Symposium: Pet Nutrition Coming of Age
[Conference Paper in Published Proceedings]Authored by: Rutherfurd, K.

Gill, HS., Rutherfurd, KJ., & Cross, ML. (2000). Bovine milk: A unique source of immunomodulatory ingredients for functional foods. In J. Buttriss, & M. Saltmarsh (Eds.) FUNCTIONAL FOODS II. (pp. 82 - 90). : Joint Conference of the British-Nutrition-Foundation/Food Chemistry Group of the Royal-Society-of-Chemistry
[Conference Paper in Published Proceedings]Authored by: Rutherfurd, K.

Rutherfurd, K., McGrath, MC., Weidgraaf, K., Thomas, DG., & Hendriks WH, .Immune enhancing potential of a canola oil-based supplement in the cat. In Proceeings of Nutrition Society of New Zealand 2008 Vol. 33 (pp. 162 - 162). , Nutrition Society of New Zealand: Nutrition Society of New Zealand
[Conference Abstract]Authored by: Rutherfurd, K., Thomas, D., Weidgraaf, K.Edited by: Brough, L.

Singh, J., Mccarthy, ., Singh, H., Wharemate, Z., & Rutherfurd, .Physico-chemical and nutritional characteristics of New Zealand Taewa.. .
[Conference]Authored by: Rutherfurd, K.

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Other

Rutherfurd Markwick, KJ. (2005, September). Fermentation and health in monogastric animals through the use of nutraceuticals. : Wageningen Business School.
[Oral Presentation]Authored by: Rutherfurd, K.

Teaching and Supervision

Teaching Statement

Current papers taught:

202.371 Human Genetics and Molecular and Clinical Diagnoses

151.231 Food Chemistry for Nutrition

151.332 Nutrition for Sports and Performance

151.718 Macronutrient Nutrition

151.708 Research Methods

Courses Coordinated

202.703 Diagnostic Clinical Biochemistry & Immunology

Contact Supervisor

Summary of Doctoral Supervision

Position	Current	Completed
Supervisor	2	1
Co-supervisor	5	2

Current Doctoral Supervision

Supervisor of:

Cameron Haswell - Doctor of Philosophy
The effect of dietary nitrate supplementation on glycaemic control in prediabetes.
Sherina Holland - Doctor of Philosophy
Interactions between MCF-7 and MDA-MB-231 breast cancer cell lines and neutrophils

Co-supervisor of:

Jia Sun - Doctor of Philosophy
Understanding the Science and Technology of Rewena Paraoa: A Traditional Maori Product
Indika Serasinghe Mudiyanselage - Doctor of Philosophy
Investigation into the development of probiotic starter culture for industrial production of sauerkraut
Kyle Southward - Doctor of Philosophy
The effects of genetics on physical, mental and perceptual responses to caffeine supplementation
Luke Stanaway - Doctor of Philosophy
The effects of nitrate supplementation on performance, metabolism and cardiovasculr function in older adults
Margreet Hekman - Doctor of Philosophy
The physiological effects of dietary moisture on cats and dogs

Completed Doctoral Supervision

Supervisor of:

2015 - Zirsha Wharemate - Doctor of Philosophy
Investigations into the Nutritional and Sensory Potential of Taewa (Maori Potatoes)

Co-supervisor of:

2013 - Ishwani Singh - Doctor of Philosophy
Optimising the performance of working dogs under New Zealand conditions
2010 - Shay Hill - Doctor of Philosophy
Changing the metabolism of dogs (Canis familiaris) and cats (Felis catus) at rest and during exercise by manipulation of dietary macronutrients

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Dr Kay Rutherfurd-Markwick

Associate Professor in Pathophysiology

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Teaching and Supervision

Teaching Statement

Courses Coordinated

Summary of Doctoral Supervision

Current Doctoral Supervision

Completed Doctoral Supervision