Maulik Mungalpara

Citation

Thesis Title
New Routes to Planar Chiral Ligands and their Use in Asymmetric Catalysis

Read article at Massey Research Online:

Biomolecules such as carbohydrates, proteins, and nucleic acids are chiral, which means they exist in one of two mirror images. Chirality is a prerequisite for life. Synthesising chiral molecules for real-life applications such as pharmaceuticals, agrochemicals, and materials is a challenging process. Mr Mungalapara’s thesis aimed to develop novel synthetic methodologies to access chiral derivatives based on [2.2]paracyclophane, a planar chiral framework. Three different methods have been successfully developed to synthesise [2.2]paracyclophane derivatives, which can act as chiral ligands for asymmetric catalysis. Research carried out during his PhD has provided new and facile routes for synthesising chiral [2.2]paracyclophane derivatives, which were previously difficult to access. Many of these derivatives are novel and could be beneficial for the wider chemistry community.

Supervisors
Associate Professor Gareth Rowlands
Professor Paul Plieger