Contact details +6469517027

Dr Thomas Lopdell PhD

Senior Research Officer - Bioinformatics

School of Agriculture and Environment

Professional

Qualifications

  • Doctor of Philosophy in Biolgical Sciences - Auckland University of Technology (2020)

Research Outputs

Journal

Lopdell, TJ., Trevarton, AJ., Moody, J., Prowse-Wilkins, C., Knowles, S., Tiplady, K., . . . Littlejohn, MD. (2024). A common regulatory haplotype doubles lactoferrin concentration in milk. Genetics Selection Evolution. 56(1)
[Journal article]Authored by: Littlejohn, M., Lopdell, T.
Yuan, C., Tang, L., Lopdell, T., Petrov, VA., Oget-Ebrad, C., Moreira, GCM., . . . Palma-Vera, S. (2023). An organism-wide ATAC-seq peak catalog for the bovine and its use to identify regulatory variants. Genome Research. 33(10), 1848-1864
[Journal article]Authored by: Littlejohn, M., Lopdell, T.
Trebes, H., Wang, Y., Reynolds, E., Tiplady, K., Harland, C., Lopdell, T., . . . Couldrey, C. (2023). Identification of candidate novel production variants on the Bos taurus chromosome X. Journal of Dairy Science. 106(11), 7799-7815
[Journal article]Authored by: Lopdell, T.
Lopdell, TJ. (2023). Using QTL to Identify Genes and Pathways Underlying the Regulation and Production of Milk Components in Cattle. Animals. 13(5)
[Journal article]Authored by: Lopdell, T.
Moody, J., Mears, E., Trevarton, AJ., Broadhurst, M., Molenaar, A., Chometon, T., . . . Snell, R. (2023). Successful editing and maintenance of lactogenic gene expression in primary bovine mammary epithelial cells. In Vitro Cellular and Developmental Biology - Animal. 59(5), 316-330
[Journal article]Authored by: Littlejohn, M., Lopdell, T.
Trevarton, AJ., Mears, ER., Moody, J., Lopdell, TJ., Chometon, TQ., Taylor, JA., . . . Snell, RG. (2023). Development of SpCas9-expressing bovine mammary epithelial cell lines. In Vitro Cellular and Developmental Biology - Animal. 59(3), 163-165
[Journal article]Authored by: Littlejohn, M., Lopdell, T.
Prowse-Wilkins, CP., Lopdell, TJ., Xiang, R., Vander Jagt, CJ., Littlejohn, MD., Chamberlain, AJ., . . . Goddard, ME. (2022). Genetic variation in histone modifications and gene expression identifies regulatory variants in the mammary gland of cattle. BMC Genomics. 23(1)
[Journal article]Authored by: Littlejohn, M., Lopdell, T.
Tiplady, KM., Lopdell, TJ., Sherlock, RG., Johnson, TJJ., Spelman, RJ., Harris, BL., . . . Garrick, DJ. (2022). Comparison of the genetic characteristics of directly measured and Fourier-transform mid-infrared-predicted bovine milk fatty acids and proteins. Journal of Dairy Science. 105(12), 9763-9791
[Journal article]Authored by: Garrick, D., Littlejohn, M., Lopdell, T.
Davis, SR., Ward, HE., Kelly, V., Palmer, D., Ankersmit-Udy, AE., Lopdell, TJ., . . . Lehnert, K. (2022). Screening for phenotypic outliers identifies an unusually low concentration of a β-lactoglobulin B protein isoform in bovine milk caused by a synonymous SNP. Genetics Selection Evolution. 54(1)
[Journal article]Authored by: Littlejohn, M., Lopdell, T.
Reynolds, EGM., Lopdell, T., Wang, Y., Tiplady, KM., Harland, CS., Johnson, TJJ., . . . Littlejohn, MD. (2022). Non-additive QTL mapping of lactation traits in 124,000 cattle reveals novel recessive loci. Genetics Selection Evolution. 54(1)
[Journal article]Authored by: Garrick, D., Littlejohn, M., Lopdell, T.
Zhou, J., Liu, L., Lopdell, TJ., Garrick, DJ., & Shi, Y. (2021). HandyCNV: Standardized Summary, Annotation, Comparison, and Visualization of Copy Number Variant, Copy Number Variation Region, and Runs of Homozygosity. Frontiers in Genetics. 12
[Journal article]Authored by: Garrick, D., Lopdell, T.
Tiplady, KM., Lopdell, TJ., Reynolds, E., Sherlock, RG., Keehan, M., Johnson, TJ., . . . Littlejohn, MD. (2021). Sequence-based genome-wide association study of individual milk mid-infrared wavenumbers in mixed-breed dairy cattle. Genetics Selection Evolution. 53(1)
[Journal article]Authored by: Garrick, D., Littlejohn, M., Lopdell, T.
Reynolds, EGM., Neeley, C., Lopdell, TJ., Keehan, M., Dittmer, K., Harland, CS., . . . Littlejohn, MD. (2021). Non-additive association analysis using proxy phenotypes identifies novel cattle syndromes. Nature Genetics. 53(7), 949-954
[Journal article]Authored by: Dittmer, K., Garrick, D., Littlejohn, M., Lopdell, T.
Fink, T., Lopdell, TJ., Tiplady, K., Handley, R., Johnson, TJJ., Spelman, RJ., . . . Littlejohn, MD. (2020). A new mechanism for a familiar mutation - bovine DGAT1 K232A modulates gene expression through multi-junction exon splice enhancement. BMC Genomics. 21(1)
[Journal article]Authored by: Littlejohn, M., Lopdell, T.
Tiplady, KM., Lopdell, TJ., Littlejohn, MD., & Garrick, DJ. (2020). The evolving role of Fourier-transform mid-infrared spectroscopy in genetic improvement of dairy cattle. Journal of Animal Science and Biotechnology. 11(1)
[Journal article]Authored by: Garrick, D., Littlejohn, M., Lopdell, T.
Johnson, T., Keehan, M., Harland, C., Lopdell, T., Spelman, RJ., Davis, SR., . . . Couldrey, C. (2019). Short communication: Identification of the pseudoautosomal region in the Hereford bovine reference genome assembly ARS-UCD1.2. Journal of Dairy Science. 102(4), 3254-3258
[Journal article]Authored by: Lopdell, T.
Lopdell, TJ., Tiplady, K., Couldrey, C., Johnson, TJJ., Keehan, M., Davis, SR., . . . Littlejohn, MD. (2019). Multiple QTL underlie milk phenotypes at the CSF2RB locus. Genetics Selection Evolution. 51(1)
[Journal article]Authored by: Littlejohn, M., Lopdell, T.
Lopdell, TJ., Hawkins, V., Couldrey, C., Tiplady, K., Davis, SR., Harris, BL., . . . Littlejohn, MD. (2019). Widespread cis-regulation of RNA editing in a large mammal. RNA. 25(3), 319-335
[Journal article]Authored by: Littlejohn, M., Lopdell, T.
Jivanji, S., Worth, G., Lopdell, TJ., Yeates, A., Couldrey, C., Reynolds, E., . . . Littlejohn, MD. (2019). Genome-wide association analysis reveals QTL and candidate mutations involved in white spotting in cattle. Genetics Selection Evolution. 51(1)
[Journal article]Authored by: Garrick, D., Littlejohn, M., Lopdell, T.
Couldrey, C., Johnson, T., Lopdell, T., Zhang, IL., Littlejohn, MD., Keehan, M., . . . Spelman, RJ. (2017). Bovine mammary gland X chromosome inactivation. Journal of Dairy Science. 100(7), 5491-5500
[Journal article]Authored by: Littlejohn, M., Lopdell, T.
Lopdell, TJ., Tiplady, K., Struchalin, M., Johnson, TJJ., Keehan, M., Sherlock, R., . . . Littlejohn, MD. (2017). DNA and RNA-sequence based GWAS highlights membrane-transport genes as key modulators of milk lactose content. BMC Genomics. 18(1)
[Journal article]Authored by: Littlejohn, M., Lopdell, T.
Fink, T., Tiplady, K., Lopdell, T., Johnson, T., Snell, RG., Spelman, RJ., . . . Littlejohn, MD. (2017). Functional confirmation of PLAG1 as the candidate causative gene underlying major pleiotropic effects on body weight and milk characteristics. Scientific Reports. 7
[Journal article]Authored by: Littlejohn, M., Lopdell, T.
Littlejohn, MD., Tiplady, K., Fink, TA., Lehnert, K., Lopdell, T., Johnson, T., . . . Spelman, RJ. (2016). Sequence-based Association Analysis Reveals an MGST1 eQTL with Pleiotropic Effects on Bovine Milk Composition. Scientific Reports. 6
[Journal article]Authored by: Littlejohn, M., Lopdell, T.
Kemper, KE., Littlejohn, MD., Lopdell, T., Hayes, BJ., Bennett, LE., Williams, RP., . . . Goddard, ME. (2016). Leveraging genetically simple traits to identify small-effect variants for complex phenotypes. BMC Genomics. 17(1)
[Journal article]Authored by: Littlejohn, M., Lopdell, T.
Littlejohn, MD., Tiplady, K., Lopdell, T., Law, TA., Scott, A., Harland, C., . . . Snell, RG. (2014). Expression variants of the lipogenic AGPAT6 gene affect diverse milk composition phenotypes in Bos taurus. PLoS ONE. 9(1)
[Journal article]Authored by: Littlejohn, M., Lopdell, T.
Littlejohn, MD., Henty, KM., Tiplady, K., Johnson, T., Harland, C., Lopdell, T., . . . Davis, SR. (2014). Functionally reciprocal mutations of the prolactin signalling pathway define hairy and slick cattle. Nature Communications. 5
[Journal article]Authored by: Garrick, D., Littlejohn, M., Lopdell, T.

Uncategorised

Zhou, J., Liu, L., Lopdell, T., Garrick, D., & Shi, Y.April
[Preprint]Authored by: Lopdell, T.
Reynolds, EGM., Lopdell, T., Wang, Y., Tiplady, K., Harland, C., Johnson, TJJ., . . . Littlejohn, M.September
[Preprint]Authored by: Lopdell, T.